Structure and function in the budding yeast nucleus
Budding yeast, like other eukaryotes, carries its genetic information on chromosomes that
are sequestered from other cellular constituents by a double membrane, which forms the …
are sequestered from other cellular constituents by a double membrane, which forms the …
Roles of DNA polymerases in replication, repair, and recombination in eukaryotes
YI Pavlov, PV Shcherbakova, IB Rogozin - International review of cytology, 2006 - Elsevier
The functioning of the eukaryotic genome depends on efficient and accurate DNA replication
and repair. The process of replication is complicated by the ongoing decomposition of DNA …
and repair. The process of replication is complicated by the ongoing decomposition of DNA …
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the …
O Chilkova, P Stenlund, I Isoz, CM Stith… - Nucleic acids …, 2007 - academic.oup.com
Saccharomyces cerevisiae DNA polymerase δ (Pol δ) and DNA polymerase ε (Pol ε) are
replicative DNA polymerases at the replication fork. Both enzymes are stimulated by PCNA …
replicative DNA polymerases at the replication fork. Both enzymes are stimulated by PCNA …
[HTML][HTML] Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories
Faithful DNA replication ensures genetic integrity in eukaryotic cells, but it is still obscure
how replication is organized in space and time within the nucleus. Using timelapse …
how replication is organized in space and time within the nucleus. Using timelapse …
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome
MD Sekedat, D Fenyö, RS Rogers… - Molecular systems …, 2010 - embopress.org
Previous studies have led to a picture wherein the replication of DNA progresses at variable
rates over different parts of the budding yeast genome. These prior experiments, focused on …
rates over different parts of the budding yeast genome. These prior experiments, focused on …
The yeast genome undergoes significant topological reorganization in quiescence
MT Rutledge, M Russo, JM Belton, J Dekker… - Nucleic acids …, 2015 - academic.oup.com
We have examined the three-dimensional organization of the yeast genome during
quiescence by a chromosome capture technique as a means of understanding how genome …
quiescence by a chromosome capture technique as a means of understanding how genome …
Genetic instability in budding and fission yeast—sources and mechanisms
A Skoneczna, A Kaniak… - FEMS microbiology …, 2015 - academic.oup.com
Cells are constantly confronted with endogenous and exogenous factors that affect their
genomes. Eons of evolution have allowed the cellular mechanisms responsible for …
genomes. Eons of evolution have allowed the cellular mechanisms responsible for …
DNA polymerases at the eukaryotic fork—20 years later
YI Pavlov, PV Shcherbakova - Mutation Research/Fundamental and …, 2010 - Elsevier
Function of the eukaryotic genome depends on efficient and accurate replication of anti-
parallel DNA strands. Eukaryotic DNA polymerases have different properties adapted to …
parallel DNA strands. Eukaryotic DNA polymerases have different properties adapted to …
G4-interacting DNA helicases and polymerases: potential therapeutic targets
KN Estep, TJ Butler, J Ding… - Current medicinal …, 2019 - ingentaconnect.com
Background: Guanine-rich DNA can fold into highly stable four-stranded DNA structures
called G-quadruplexes (G4). In recent years, the G-quadruplex field has blossomed as new …
called G-quadruplexes (G4). In recent years, the G-quadruplex field has blossomed as new …
DNA polymerases and human diseases
JB Sweasy, JM Lauper, KA Eckert - Radiation research, 2006 - meridian.allenpress.com
Abstract Sweasy, JB, Lauper, JM and Eckert, KA DNA Polymerases and Human Diseases.
Radiat. Res. 166, 693–714 (2006). DNA polymerases function in DNA replication, repair …
Radiat. Res. 166, 693–714 (2006). DNA polymerases function in DNA replication, repair …