[HTML][HTML] Focus: sex and gender health: Marijuana, the Endocannabinoid System and the female reproductive system

LK Brents - The Yale journal of biology and medicine, 2016 - ncbi.nlm.nih.gov
Marijuana use among women is highly prevalent, but the societal conversation on marijuana
rarely focuses on how marijuana affects female reproduction and endocrinology. This article …

The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders

J Maia, BM Fonseca, N Teixeira… - Human Reproduction …, 2020 - academic.oup.com
BACKGROUND The endocannabinoid system (ECS) consists of the cannabinoid receptors
CB1 and CB2, the main endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol …

Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update

P Morales, L Hernandez-Folgado, P Goya… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Modulation of the CB2 receptor is an interesting approach for pain and
inflammation, arthritis, addictions, neuroprotection, and cancer, among other possible …

Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts

P Alves, C Amaral, N Teixeira, G Correia-da-Silva - Archives of toxicology, 2021 - Springer
Cannabidiol (CBD) is a constituent of Cannabis sativa without psychotropic activity, whose
medical benefits have been recognised. However, little is known about the potential toxic …

The impact of early life exposure to cannabis: The role of the endocannabinoid system

AA Martínez-Peña, GA Perono, SA Gritis… - International Journal of …, 2021 - mdpi.com
Cannabis use during pregnancy has continued to rise, particularly in developed countries,
as a result of the trend towards legalization and lack of consistent, evidence-based …

Lipid endocannabinoids in energy metabolism, stress and developmental programming

MM Almeida, CP Dias-Rocha, C Calviño… - Molecular and Cellular …, 2022 - Elsevier
The endocannabinoid system (ECS) regulates brain development and function, energy
metabolism and stress in a sex-, age-and tissue-dependent manner. The ECS comprises …

The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells

J Maia, BM Fonseca, N Teixeira… - … and Essential Fatty Acids, 2022 - Elsevier
The interest on the endocannabinoid system (ECS) in human reproduction has grown due to
its involvement in placenta development, which led to growing concerns over pregnant …

Scrutinising the regulators of syncytialization and their expression in pregnancy-related conditions

MA Costa - Molecular and cellular endocrinology, 2016 - Elsevier
The placenta is important for the success of gestation and foetal development. In fact, this
specialized pregnancy organ is essential for foetal nourishment, support, and protection. In …

Cannabinoids and the placenta: receptors, signaling and outcomes

ACE Rokeby, BV Natale, DRC Natale - Placenta, 2023 - Elsevier
Cannabis use during pregnancy is increasing. The improvement of pregnancy-related
symptoms including morning sickness and management of mood and stress are among the …

The psychoactive compound of Cannabis sativa, Δ9-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover

MA Costa, BM Fonseca, F Marques, NA Teixeira… - Toxicology, 2015 - Elsevier
The noxious effects of cannabis consumption for fertility and pregnancy outcome are
recognized for years. Its consumption during gestation is associated with alterations in foetal …