Aptamers are single‐stranded oligonucleotides that bind to targets with high affinity and
selectivity. Their use as molecular recognition elements has emerged as a viable approach …

Small molecules play a major role in the human body and as drugs, toxins, and chemicals.
Tools to detect and quantify them are therefore in high demand. This review will give an …

Aptamers, including DNA, RNA and peptide aptamers, are a group of promising recognition
units that can specifically bind to target molecules and cells. Due to their excellent specificity …

Over the last four decades nucleic acid hybridization techniques have been widely used for
the detection of specific nucleic acid sequences. In this approach a 15-nucleotide or longer …

Cyanine dyes are widely used as fluorescent probes in biophysics and medical biochemistry
due to their unique photophysical and photochemical properties (their photonics). This …

C-di-GMP regulates important processes involved in biofilm formation and virulence factors
production in several bacteria. Herein we report a simple fluorescent strategy that allows for …

Nucleic acid aptamers are short synthetic DNA or RNA sequences that can bind to a wide
range of targets with high affinity and specificity. In recent years, aptamers have attracted …

Therapeutic molecules can be classified as low-, middle-and high-molecular weight drugs
depending on their molecular masses. Antibodies represent high-molecular weight drugs …

Aptamers are short, single‐stranded nucleic acid sequences that are selected in vitro from
large oligonucleotide libraries based on their high affinity to a target molecule. Hence …

AML1 (RUNX1) is a key transcription factor for hematopoiesis that binds to the Runt-binding
double-stranded DNA element (RDE) of target genes through its N-terminal Runt domain …