[HTML][HTML] The life and works of S100P-from conception to cancer

F Prica, T Radon, Y Cheng… - American journal of …, 2016 - ncbi.nlm.nih.gov
Since its discovery in 1992, the small, 10.4 kDa calcium-binding protein S100P has gained
the attention of researchers from different scientific fields due to its potential roles in both …

[HTML][HTML] Decoding the role of S100 proteins in mammary gland regulation and their role in breast cancer metastasis

P Singh, SA Ali - Advances in Cancer Biology-Metastasis, 2023 - Elsevier
S100 proteins have emerged as key regulators in the mammary gland and have been
implicated in breast cancer development and metastasis. This review provides a …

High-molecular-weight hyaluronan is a hippo pathway ligand directing cell density-dependent growth inhibition via PAR1b

T Ooki, N Murata-Kamiya, A Takahashi-Kanemitsu… - Developmental cell, 2019 - cell.com
High-molecular-weight hyaluronan, a major component of the extracellular matrix, is anti-
oncogenic, whereas low-molecular-weight hyaluronan is pro-oncogenic, though the …

Distinct prognostic values of S100 mRNA expression in breast cancer

S Zhang, Z Wang, W Liu, R Lei, J Shan, L Li, X Wang - Scientific reports, 2017 - nature.com
S100 family genes encode low molecular weight, acidic-Ca2+ binding proteins implicating
in a wide spectrum of biological processes. S100 family contains at least 20 members, most …

Calcium-binding protein S100P promotes tumor progression but enhances chemosensitivity in breast cancer

Y Cong, Y Cui, S Wang, L Jiang, J Cao, S Zhu… - Frontiers in …, 2020 - frontiersin.org
Background Chemoresistance remains one of the obstacles to overcome in the treatment of
breast cancer. S100 calcium-binding protein P (S100P) has been observed to be …

Gene expression profiling of breast cancer in Lebanese women

J Makoukji, NJ Makhoul, M Khalil, S El-Sitt, ES Aldin… - Scientific reports, 2016 - nature.com
Breast cancer is commonest cancer in women worldwide. Elucidation of underlying biology
and molecular pathways is necessary for improving therapeutic options and clinical …

S100P and Ezrin promote trans-endothelial migration of triple negative breast cancer cells

K Kikuchi, KM McNamara, Y Miki, E Iwabuchi, A Kanai… - Cellular Oncology, 2019 - Springer
Purpose Triple negative breast cancer (TNBC) patients generally have an adverse clinical
outcome because their tumors often recur and metastasize to distant sites in the first 3 years …

Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer

P Martinez-Morales, IM Cruz, L Roa-de la Cruz… - PeerJ, 2021 - peerj.com
Background Dysregulation of glycogene expression in cancer can lead to aberrant glycan
expression, which can promote tumorigenesis. Cervical cancer (CC) displays an increased …

[HTML][HTML] Aberrant calcium signalling downstream of mutations in TP53 and the PI3K/AKT pathway genes promotes disease progression and therapy resistance in triple …

AJ Eustace, MJ Lee, G Colley, J Roban… - Cancer Drug …, 2022 - ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) is characterized as an aggressive form of breast
cancer (BC) associated with poor patient outcomes. For the majority of patients, there is a …

The suppressive role of HYAL1 and HYAL2 in the metastasis of colorectal cancer

Z Jin, G Zhang, Y Liu, Y He, C Yang… - Journal of …, 2019 - Wiley Online Library
Abstract Background Hyaluronidases (HAases), enzymes that degrade hyaluronan, have
been widely investigated in cancer biology. However, whether HAases serve as tumor …