Role of phenolic compounds in human disease: current knowledge and future prospects

MM Rahman, MS Rahaman, MR Islam, F Rahman… - Molecules, 2021 - mdpi.com
Inflammation is a natural protective mechanism that occurs when the body's tissue
homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune …

Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer's disease

NR Jabir, FR Khan, S Tabrez - CNS neuroscience & …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive irreversible neurodegenerative disorder
characterized by excessive deposition of β‐amyloid (Aβ) oligomers, and neurofibrillary …

In-vitro studies of Curcumin-β-cyclodextrin inclusion complex as sustained release system

P Arya, N Raghav - Journal of Molecular Structure, 2021 - Elsevier
Curcumin has always gained attention due to its diverse medicinal properties; concerns are
related to its metabolism and aqueous solubility. Researchers are putting forth persistent …

High performance curcumin subcritical water extraction from turmeric (Curcuma longa L.)

MV Kiamahalleh, G Najafpour-Darzi… - … of Chromatography B, 2016 - Elsevier
Curcumin is a hydrophobic polyphenolic compound derived from turmeric rhizome, which
consists about 2–5% of the total rhizome content and is a more valuable component of …

Extraction of bioactive compounds from Curcuma longa L. using deep eutectic solvents: In vitro and in vivo biological activities

G Oliveira, C Marques, A de Oliveira… - Innovative Food Science …, 2021 - Elsevier
In this work, deep eutectic solvents (DES-based menthol and cholinium chloride) and the
ethanol, temperature, and times were selected to extract bioactive compounds from the …

In vitro and in vivo evaluation of enzymatic and antioxidant activity, cytotoxicity and genotoxicity of curcumin-loaded solid dispersions

IS de Sá, AP Peron, FV Leimann, GN Bressan… - Food and Chemical …, 2019 - Elsevier
Curcumin, the main bioactive polyphenolic compound in Curcuma longa L. rhizomes has a
wide range of bioactive properties. Curcumin presents low solubility in water and thus …

Revealing the molecular interplay of curcumin as Culex pipiens Acetylcholine esterase 1 (AChE1) inhibitor

P Rao, D Goswami, RM Rawal - Scientific Reports, 2021 - nature.com
Emergence of vector borne diseases has continued to take toll on millions of lives since its
inception. The use of insecticides began as vector control strategy in the early 1900's but the …

Curcumin incorporated PVA‐borax dual delivery hydrogels as potential wound dressing materials—Correlation between viscoelastic properties and curcumin release …

G Rezvan, G Pircheraghi… - Journal of Applied …, 2018 - Wiley Online Library
ABSTRACT Poly (vinyl alcohol)(PVA) is a biocompatible polymer which can be physically
crosslinked by Borax to form hydrogel. PVA‐Borax (PB) hydrogel is a promising candidate …

Molecular insights on ar-turmerone as a structural, functional and pharmacophoric analogue of synthetic mosquito repellent DEET by comprehensive computational …

P Rao, D Goswami, RM Rawal - Scientific Reports, 2022 - nature.com
Mosquitoes are vectors for a variety of infectious illnesses, and chemical synthetic
insecticides have made it possible to control them effectively. Mosquito repellents are a …

The nanoencapsulation of curcuminoids extracted from Curcuma longa L. and an evaluation of their cytotoxic, enzymatic, antioxidant and anti-inflammatory activities

PDF Dos Santos, CRL Francisco, A Coqueiro… - Food & function, 2019 - pubs.rsc.org
Curcumin, bisdemethoxycurcumin and demethoxycurcumin are the main curcuminoids
present in Curcuma longa L. and are known for their bioactivity. However, their low water …