The human physiological response “to stress” includes all metabolic and hormonal changes
produced by a traumatic event at the micro or macro cellular levels. The main goal of the …

Abstract Oliceridine (Olinvyk® Trevena, PA, USA) was approved by the United States Food
and Drug Administration for clinical use on Aug 8, 2020. Even though, the indication of its …

strategies to optimize patient outcomes. We present a case of a 32-year-old male who
suffered severe TBI following a motorcycle accident, emphasizing the complexity and …

Patients with sepsis often require emergency intubation. In emergency departments (EDs),
rapid-sequence intubation with a single-dose induction agent is standard practice, but the …

Rationale: Uncertainty remains regarding the risks associated with single-dose use of
etomidate. Objectives: To assess the use of etomidate in critically ill patients and compare …

Background There is limited evidence regarding factors associated with mortality in septic
patients receiving etomidate. This study aimed to determine independent pre-intubation …

Background: Severe traumatic brain injury is a leading cause of morbidity and mortality
among young people around the world. Prehospital care focuses on the prevention and …

Objective: To review the efficacy, safety, and place in therapy of fentanyl as an induction
agent for rapid sequence intubation (RSI) in critically ill patients. Data Sources: A …

According to the 2016 Society of Critical Care Medicine/European Society of Intensive Care
Medicine, sepsis is defined as a life-threatening response to infection that leads to organ …

Background The risk of adrenal insufficiency (AI) in using single-dose etomidate for
intubation among patients with sepsis remains controversial. Our aim was to assess the …