Over the last two and a half decades, photoacoustic (PA) imaging has become an important
area of research in biomedical optics. Combining the high contrast of optical imaging with …

Photoacoustic imaging can be used to extract functional information at the molecular level
for imaging the whole body of small animals in vivo. However, the use of a mechanical …

In this study, we investigated the feasibility of using photoacoustic time-frequency spectral
analysis (PA-TFSA) for evaluating the bone mineral density (BMD) and bone structure …

Vascular disrupting agents disrupt tumor vessels, blocking the nutritional and oxygen supply
tumors need to thrive. This is achieved by damaging the endothelium lining of blood vessels …

The development of novel anticancer therapies warrants the parallel development of
biomarkers that can quantify their effectiveness. Photoacoustic imaging has the potential to …

The tubular structures and dendritic distributions of blood vessels emit anisotropic
photoacoustic (PA) signals with different intensities and frequency components at different …

A photoacoustic (PA) graphic equalization (PAGE) algorithm was developed to characterize
the relative size of optical absorbing aggregates. This technique divides the PA signal into …

Blood vessels are crucial for the survival and growth of solid tumours by continuously
supplying the tumour cells with oxygen and nutrients. Selectively targeting tumour cells has …

This dissertation describes the development of functional and structural photoacoustic (PA)
imaging biomarkers that can be used to monitor cancer treatment response and potentially …