The BCL-2 family of proteins integrates signals that trigger either cell survival or apoptosis.
The balance between pro-survival and pro-apoptotic proteins is important for tissue …

Oral leukoplakia (OLK) and its more aggressive clinical variant proliferative verrucous
leukoplakia (PVL) remain enigmatic disorders clinically and histopathologically. Despite …

Background Autophagy, a highly conserved self-digesting process, has been deeply
involved in the development and progression of oral squamous cell carcinoma (OSCC) …

The aim of this study is to elucidate whether and how miR-107 participates in the modulation
of paclitaxel sensitivity in non small cell lung cancer (NSCLC). By qRT-PCR, we found that …

Lung cancer as the leading cause of cancer related mortality is always one of the main
global health challenges. Despite the recent progresses in therapeutic methods, the …

The goals of present research are to investigate if the genetic polymorphisms in the caspase-
1 (CASP1) gene are associated with the risk of rheumatoid arthritis (RA) and the clinical …

Selenium compounds have been widely investigated as novel anticancer agents due to high
efficacy and selectivity against cancer cells in recent years. This study aimed to research the …

Abstract mtDNA is the closed circular, ds-DNA present in mitochondria of eukaryotic cells
and are inherited maternally. Besides being the power house of the cell, mitochondria are …

Oral cancer is caused by a combination of multiple extrinsic and intrinsic risk factors acting
over a long period of time. Tobacco is the primary etiological factor for oral cancer; however …

Oral squamous cell carcinoma (OSCC) is a predominant type of head and neck cancer in
the Indian subcontinent, mostly observed among tobacco and/or alcohol users. Oral …