Significant progress has been made in the treatment of spinal cord injury (SCI). Advances in
post-trauma management and intensive rehabilitation have significantly improved the …

Alzheimer's disease (AD) is known as the most fatal chronic neurodegenerative disease in
adults along with progressive loss of memory and other cognitive function disorders. Cyclin …

We report a comprehensive proteogenomics analysis, including whole-genome sequencing,
RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 …

In the nervous system, only one type of neuron–glial synapse is known to exist: that between
neurons and oligodendrocyte precursor cells (OPCs), yet their composition, assembly …

Regulation of myelination by oligodendrocytes in the CNS has important consequences for
higher-order nervous system function (eg,[1–4]), and there is growing consensus that …

Locomotor behaviors are critical for survival and enable animals to navigate their
environment, find food and evade predators. The circuits in the brain and spinal cord that …

Synapsins (Syns) are phosphoproteins strongly involved in neuronal development and
neurotransmitter release. Three distinct genes SYN1, SYN2 and SYN3, with elevated …

Highlights•Mechanisms of cargo sorting in axons and dendrites.•Mechanisms of cargo
motility and anchoring.•Mechanisms of cargo delivery and capturing.Neuronal trafficking is …

Lewy bodies, a pathological hallmark of Parkinson's disease (PD), contain aggregated
alpha-synuclein (αSyn), which is found in several modified forms and can be discovered …

Cyclin-dependent kinase-5 (Cdk5) was reported to downscale neurotransmission by
sequestering synaptic vesicles (SVs) in the release-reluctant resting pool, but the molecular …