Iron is essential for the survival of most bacteria but presents a significant challenge given its
limited bioavailability. Furthermore, the toxicity of iron combined with the need to maintain …

Deviant levels of available heme and related molecules can result from pathological
situations such as impaired heme biosynthesis or increased hemolysis as a consequence of …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

Pseudomonas aeruginosa is an opportunistic bacterium that causes life-threatening
infections in immunocompromised patients. In infection, it uses heme as a primary iron …

The voltage-dependent anion channel (VDAC) is an essential protein in the eukaryotic outer
mitochondrial membrane, providing the pore for substrate diffusion. Three high-resolution …

Recent progress in genetics, fed by the burst in genome sequence data, has led to the
identification of a host of novel bacterial heme proteins that are now being characterized in …

We have recently investigated the aggregation behavior of zwitterionic n-dodecyl
phosphocholine in the presence of high salt. As double logarithmic Corrin–Harkins plots of …

Iron is an essential nutrient for the bacterial pathogen Staphylococcus aureus. Heme in
hemoglobin (Hb) is the most abundant source of iron in the human body and during …

All but a few bacterial species have an absolute need for heme, and most are able to
synthesize it via a pathway that is highly conserved among all life domains. Because heme …

Background The occurrence of free organismal heme can either contribute to serious
diseases or beneficially regulate important physiological processes. Research on transient …