Repeated drug use can change dopamine (DA) function in ways that promote the
development and persistence of addiction, but in what direction? By one view, drug use …

Abnormalities in reward processing are crucial symptoms of major depressive disorder
(MDD) and schizophrenia (SCH). Recent neuroscientific findings regarding MDD have led to …

Computational approaches are increasingly being used to model behavioral and neural
processes in mood and anxiety disorders. Here we explore the extent to which the …

A wide homology between human and macaque striatum is often assumed as in both the
striatum is involved in cognition, emotion and executive functions. However, differences in …

Cognitive neuroscience depends on the use of blood oxygenation level-dependent (BOLD)
functional magnetic resonance imaging (fMRI) to probe brain function. Although commonly …

Progress in the development of technologies for the real-time monitoring of neurotransmitter
dynamics has provided researchers with effective tools for the exploration of etiology and …

Background Mesolimbic dopamine system dysfunction is believed to contribute to major
depressive disorder (MDD), but molecular neuroimaging of striatal dopamine …

Neuroimaging studies have identified a variety of brain regions whose activity predicts
substance use (ie, relapse) in patients with substance use disorder (SUD), suggesting that …

The vascular contributions of neurotransmitters to the hemodynamic response are gaining
more attention in neuroimaging studies, as many neurotransmitters are vasomodulatory. To …

To date, the spatiotemporal release of specific neurotransmitters at physiological levels in
the human brain cannot be detected. Here, we present a method that relates minute-by …