Exploring viral neuropathic pain: Molecular mechanisms and therapeutic implications
S Xu, H Li, Z Ai, R Guo, H Cheng, Y Wang - Plos Pathogens, 2024 - journals.plos.org
As the Coronavirus Disease 2019 (COVID-19) pandemic continues, there is a growing
concern regarding the relationship between viral infections and neuropathic pain. Chronic …
concern regarding the relationship between viral infections and neuropathic pain. Chronic …
[HTML][HTML] Ginkgolide B effectively mitigates neuropathic pain by suppressing the activation of the NLRP3 inflammasome through the induction of mitophagy in rats
JH Liang, H Yu, CP Xia, YH Zheng, Z Zhang… - Biomedicine & …, 2024 - Elsevier
Neuropathic pain is a pathological state induced by the aberrant generation of pain signals
within the nervous system. Ginkgolide B (GB), an active component found of Ginkgo. biloba …
within the nervous system. Ginkgolide B (GB), an active component found of Ginkgo. biloba …
Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding
BA Benita, KM Koss - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Uncontrolled and chronic inflammatory states in the Central Nervous System (CNS) are the
hallmark of neurodegenerative pathology and every injury or stroke-related insult. The key …
hallmark of neurodegenerative pathology and every injury or stroke-related insult. The key …
Development and validation of clinically Mimicable model of frostbite injury-induced chronic pain
Frostbite, a debilitating condition, significantly affects the well-being of military veterans and
high-altitude residents, causing severe clinical complications such as chronic pain that …
high-altitude residents, causing severe clinical complications such as chronic pain that …
Mahuang Fuzi Xixin decoction: A potent analgesic for neuropathic pain targeting the NMDAR2B/CaMKIIα/ERK/CREB pathway
Y Chai, S He, D Liang, C Gu, Q Gong, L Long, P Chen… - Heliyon, 2024 - cell.com
Neuropathic pain (NeP) is a condition charactesized by nervous system injury or dysfunction
that affects a significant portion of the population. Current treatments are ineffective …
that affects a significant portion of the population. Current treatments are ineffective …
[HTML][HTML] Statins ameliorate oxaliplatin-and paclitaxel-induced peripheral neuropathy via glutathione S-transferase
F Aizawa, H Kajimoto, A Okabayashi… - Neurochemistry …, 2024 - Elsevier
Some therapeutic agents have been found to have effects beyond their primary indications.
Peripheral neuropathy, a common side effect of chemotherapy, remains inadequately …
Peripheral neuropathy, a common side effect of chemotherapy, remains inadequately …
Dorsal root ganglion inflammation by oxaliplatin toxicity: DPEP1 as possible target for peripheral neuropathy prevention
K Álvarez-Tosco, R González-Fernández… - BMC neuroscience, 2024 - Springer
Background Peripheral neuropathy (PN) constitutes a dose-limiting side effect of oxaliplatin
chemotherapy that often compromises the efficacy of antineoplastic treatments. Sensory …
chemotherapy that often compromises the efficacy of antineoplastic treatments. Sensory …
Identification of Key Genes and Pathways in Oxaliplatin-Induced Neuropathic Pain Through Bioinformatic Analysis
Y Lou, X Xu, R Wang, D Yao - Journal of Pain Research, 2024 - Taylor & Francis
Background The mechanism of Chemotherapy-induced neuropathic pain (NP) remains
obscure. This study was aimed to uncover the key genes as well as protein networks that …
obscure. This study was aimed to uncover the key genes as well as protein networks that …