Multifaceted role of PRDM proteins in human cancer
The PR/SET domain family (PRDM) comprise a family of genes whose protein products
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …
share a conserved N-terminal PR [PRDI-BF1 (positive regulatory domain I-binding factor 1) …
[HTML][HTML] Deciphering the Potentials of Cardamom in Cancer Prevention and Therapy: From Kitchen to Clinic
S Bano, A Majumder, A Srivastava, KB Nayak - Biomolecules, 2024 - mdpi.com
Cardamom (cardamum) is a spice produced from the seeds of several Elettaria and
Amomum plants of the Zingiberaceae family. Cardamom has been demonstrated to offer …
Amomum plants of the Zingiberaceae family. Cardamom has been demonstrated to offer …
Matrine triggers colon cancer cell apoptosis and G0/G1 cell cycle arrest via mediation of microRNA‐22
J Liu, Y Guo, J Cao - Phytotherapy Research, 2020 - Wiley Online Library
Matrine (MAT) is an alkaloid in the dried roots of Sophora flavescens. The antitumor activity
has been testified in colon cancer. Howbeit, the latent mechanism is still indistinct. The …
has been testified in colon cancer. Howbeit, the latent mechanism is still indistinct. The …
Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex
D Ivanochko, L Halabelian, E Henderson… - Nucleic acids …, 2019 - academic.oup.com
Aberrant isoform expression of chromatin-associated proteins can induce epigenetic
programs related to disease. The MDS1 and EVI1 complex locus (MECOM) encodes …
programs related to disease. The MDS1 and EVI1 complex locus (MECOM) encodes …
EVI1 promotes epithelial-to-mesenchymal transition, cancer stem cell features and chemo−/radioresistance in nasopharyngeal carcinoma
Y Lu, Y Liang, X Zheng, X Deng, W Huang… - Journal of Experimental & …, 2019 - Springer
Background Aberrant EVI1 expression is frequently reported in cancer studies; however, its
role in nasopharyngeal carcinoma (NPC) has not been examined in detail. The aim of the …
role in nasopharyngeal carcinoma (NPC) has not been examined in detail. The aim of the …
EVI1 in leukemia and solid tumors
B Liang, J Wang - Cancers, 2020 - mdpi.com
Simple Summary Ecotropic viral integration site 1 (EVI1) is transcriptionally activated in a
subset of myeloid leukemias. Since its discovery, other isoforms of EVI1 have been …
subset of myeloid leukemias. Since its discovery, other isoforms of EVI1 have been …
EVI1 as a Marker for Lymph Node Metastasis in HNSCC
C Idel, J Ribbat-Idel, P Kuppler, R Krupar… - International Journal of …, 2020 - mdpi.com
Background: HNSCC is the sixth most common cancer in humans and has still a very poor
prognosis. The treatment methods so far are very often associated with mutilation and …
prognosis. The treatment methods so far are very often associated with mutilation and …
EVI1 promotes metastasis by downregulating TIMP2 in metastatic colon and breast cancer cells
Ecotropic viral integration site-1 (EVI1) is an oncogenic zinc finger transcription factor whose
expression is frequently upregulated in a variety of cancers, including both myeloid …
expression is frequently upregulated in a variety of cancers, including both myeloid …
AKT inhibition sensitizes EVI1 expressing colon cancer cells to irinotecan therapy by regulating the Akt/mTOR axis
Purpose Ecotropic viral integration site 1 (EVI1) is an oncogenic transcription factor that has
been attributed to chemotherapy resistance in different cancers. As yet, however, its role in …
been attributed to chemotherapy resistance in different cancers. As yet, however, its role in …
[HTML][HTML] The Pivotal Role of One-Carbon Metabolism in Neoplastic Progression During the Aging Process
A Majumder, S Bano, KB Nayak - Biomolecules, 2024 - mdpi.com
One-carbon (1C) metabolism is a complex network of metabolic reactions closely related to
producing 1C units (as methyl groups) and utilizing them for different anabolic processes …
producing 1C units (as methyl groups) and utilizing them for different anabolic processes …