Introduction Productivity loss may contribute to a large proportion of costs of health
conditions in an economic evaluation from a societal perspective, but there is currently a …

An important issue in economic evaluations is determining whether all relevant impacts are
considered, given the perspective chosen for the analysis. Acknowledging that patients are …

Early diagnosis of genetic rare diseases is an unmet need in Brazil, where an estimated 10–
13 million people live with these conditions. Increased use of chromosome microarray …

(1) Background: Any disturbance in the pharmaceutical supply chain (PSC) can disrupt the
supply of medicines and affect the efficiency of health systems. Due to shortages in the …

Background The economic burden of diabetes from a societal perspective is well
documented in the cost-of-illness literature. However, the effect of considering social costs in …

Research has demonstrated that some exercise programs are effective for reducing fall rates
in community-dwelling older people; however, the literature is limited in providing clear …

Background Multiple sclerosis imposes a heavy burden on the person who suffers from it
and on the relatives, due to the caregiving load involved. The objective was to analyse …

The article deals with one of the effects of health inequalities and gaps in access to
treatments for rare diseases, namely health-driven emigration. The purpose of the paper is …

Background/objective Sexually transmitted infections (STIs) not only have an impact on the
health sector but also the private resources of those affected, their families and other sectors …

Introduction Evaluating rare disease interventions poses challenges for HTA agencies,
including uncertainties and ethical issues and tensions. INESSS has recently adopted a …