DNA methylation change is known to play a crucial role in early gastric carcinogenesis. The
present study aimed to identify and validate the correlation between differentially methylated …

Central neurocytomas (CNs) are rare intraventricular tumors presenting a favorable
prognosis after surgery. Their transcriptomic profile is poorly characterized. We performed a …

Meningiomas (MGMs) are currently classified into grades I, II, and III. High-grade tumors are
correlated with decreased survival rates and increased recurrence rates. The current …

Integrin is important in migration and metastasis of tumor cells. Changes of integrin
expression and distribution will cause an alteration of cellular adhesion and migration …

Clear cell renal cell carcinoma (ccRCC) is the most prevalent type of RCC; however,
prognostic prediction tools for ccRCC are scant. Developing mRNA or long non‑coding RNA …

Among negatively charged lipids, sulfoglycolipids are known to be expressed by specific cell
populations and to be involved in their functions, including in adhesion with functional …

Background Deep learning architectures have advanced genotype-phenotype mappings
with precision but often obscure the roles of specific genes and their interactions. Our …

Colorectal cancer (CRC) is a leading cause of cancer death in the United States. Standard
treatment for advanced-stage CRC for decades has included 5-fluorouracil–based …

BACKGROUND: 3′-Sulfo-Lea is known to be the potent ligand of E-selectin which is
important in cell adhesion and migration. Yet the significance of serum 3′-sulfo-Lea has not …

Among sulphated glycans, little is known about 3′-sulphation because of the lack of useful
probes. In the course of molecular engineering of a fungal galectin from Agrocybe …