Engineering bacteria for diagnostic and therapeutic applications

DT Riglar, PA Silver - Nature Reviews Microbiology, 2018 - nature.com
Our ability to generate bacterial strains with unique and increasingly complex functions has
rapidly expanded in recent times. The capacity for DNA synthesis is increasing and costing …

The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology

M Galdzicki, KP Clancy, E Oberortner, M Pocock… - Nature …, 2014 - nature.com
The re-use of previously validated designs is critical to the evolution of synthetic biology from
a research discipline to an engineering practice. Here we describe the Synthetic Biology …

Design, implementation and practice of JBEI-ICE: an open source biological part registry platform and tools

TS Ham, Z Dmytriv, H Plahar, J Chen… - Nucleic acids …, 2012 - academic.oup.com
Abstract The Joint BioEnergy Institute Inventory of Composable Elements (JBEI-ICEs) is an
open source registry platform for managing information about biological parts. It is capable …

Cyberbiosecurity: from naive trust to risk awareness

J Peccoud, JE Gallegos, R Murch, WG Buchholz… - Trends in …, 2018 - cell.com
The cyber–physical nature of biotechnology raises unprecedented security concerns.
Computers can be compromised by encoding malware in DNA sequences, and biological …

SynBioHub: a standards-enabled design repository for synthetic biology

JA McLaughlin, CJ Myers, Z Zundel, G Mısırlı… - ACS synthetic …, 2018 - ACS Publications
The SynBioHub repository (https://synbiohub. org) is an open-source software project that
facilitates the sharing of information about engineered biological systems. SynBioHub …

One-pot DNA construction for synthetic biology: the Modular Overlap-Directed Assembly with Linkers (MODAL) strategy

A Casini, JT MacDonald, JD Jonghe… - Nucleic acids …, 2014 - academic.oup.com
Overlap-directed DNA assembly methods allow multiple DNA parts to be assembled
together in one reaction. These methods, which rely on sequence homology between the …

Standardization in synthetic biology: an engineering discipline coming of age

T Decoene, B De Paepe, J Maertens… - Critical reviews in …, 2018 - Taylor & Francis
Background: Leaping DNA read-and-write technologies, and extensive automation and
miniaturization are radically transforming the field of biological experimentation by providing …

No assembly required: Time for stronger, simpler publishing standards for DNA sequences

BW Thuronyi, EA DeBenedictis, JE Barrick - Plos Biology, 2023 - journals.plos.org
No assembly required: Time for stronger, simpler publishing standards for DNA sequences |
PLOS Biology Skip to main content Advertisement PLOS Biology Browse Current Issue …

Cryptographic approaches to authenticating synthetic DNA sequences

CT Berezin, S Peccoud, DM Kar, J Peccoud - Trends in Biotechnology, 2024 - cell.com
In a bioeconomy that relies on synthetic DNA sequences, the ability to ensure their
authenticity is critical. DNA watermarks can encode identifying data in short sequences and …

Functional genetic elements for controlling gene expression in Cupriavidus necator H16

S Alagesan, EKR Hanko, N Malys… - Applied and …, 2018 - Am Soc Microbiol
ABSTRACT A robust and predictable control of gene expression plays an important role in
synthetic biology and biotechnology applications. Development and quantitative evaluation …