Obesity is defined as chronic, low-grade inflammation within specific tissues. Given the
escalating prevalence of obesity among individuals of all ages, obesity has reached …

Simvastatin, a blockbuster drug for treating hypercholesterolemia, has multifactorial benefits
as an antimicrobial agent and plays a preventative role in reducing the incidence of …

Glioma is the most common primary malignant tumor of the nervous system that starts in the
glial cells. Its high invasiveness and recurrence pose major challenges to its effective …

Down syndrome (DS) is a complex chromosomal disorder considered as a genetically
determined form of Alzheimer's disease (AD). Maintenance of brain cholesterol homeostasis …

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder in elderly. The
neurotoxicant trimethyltin (TMT) induces neurodegenerative changes, as observed in AD …

Statins are well-tolerated and widely available lipid-lowering medications with
neuroprotective effects against traumatic brain injury (TBI). However, whether delayed statin …

Despite growing interest in the preventive effects of statins, as lipid-lowering agents, on
migraine attacks, comprehensive nationwide studies comparing migraine likelihood …

Simvastatin is a widely used statin medication that is commonly prescribed to lower
cholesterol levels and reduce the risk of cardiovascular events. It is marketed under the …

Rhabdomyosarcoma is a cancer arising from arrested myogenic differentiation, seen mainly
in children or adolescents. Metastatic rhabdomyosarcoma is often fatal even with aggressive …

Rett syndrome (RTT) is a progressive neurodevelopmental disorder without an available
cure. It is a rare disease but is known as one of the most common causes of intellectual …