In 1997 for the first time, survivin was described by Amborsini et al. as an anti-apoptotic protein. Subsequent studies revealed that survivin is a multifunctional protein that plays …
Y Lei, Z Geng, W Guo-Jun, W He, Y Jian-Lin - Molecular and cellular …, 2010 - Springer
Survivin, an important inhibitor of apoptosis, has been found to play an important role in the initiation, progression, and chemoradioresistance of human malignancies. Previously, we …
T Nakahara, K Yamanaka, S Hatakeyama… - Anti-cancer …, 2011 - journals.lww.com
Survivin, an apoptotic inhibitor, is overexpressed in the majority of human tumor types and represents a novel target for anticancer therapy. Taxanes induce a mitotic cell-cycle block …
M Mojarrad, M Moghbeli - Molecular genetics & genomic …, 2020 - Wiley Online Library
Background Bladder cancer (BC) is the sixth common cancer among Iranians. Various risk factors such as smoking, body mass index, chronic infection, age, and genetic factors are …
J Gaytan-Cervantes, C Gonzalez-Torres… - Journal of Biological …, 2017 - ASBMB
Messenger RNA alternative splicing (AS) regulates the expression of a variety of genes involved in both physiological and pathological processes. AS of the anti-apoptotic and …
G Kapellos, K Polonifi, D Farmakis… - Anticancer …, 2013 - ar.iiarjournals.org
Background: Survivin, an apoptosis inhibitor protein, has multiple functions that favor cancer cell survival. We sought to determine survivin levels in blood samples and biopsies from …
L Izquierdo, L Mengual, C Gazquez… - BJU …, 2010 - Wiley Online Library
OBJECTIVES To assess gene‐expression patterns of BIRC5, FGFR3, IGF2, KRT20, UPK2, EBF1, CDH1, FXYD3, HTERT, TP53, AGR2, HER2 and VEGF, widely known markers of …
NK Jacob, JV Cooley, K Shirai… - OncoTargets and …, 2012 - Taylor & Francis
Survivin is a critical regulator of mitosis, and an inhibitor of apoptosis which is overexpressed in almost all cancers. In the current study, cell cycle profiles of normal …
H Kitamura, T Torigoe, Y Hirohashi, H Asanuma… - Virchows Archiv, 2013 - Springer
Survivin, a member of the inhibitor of apoptosis protein gene family, inhibits apoptosis and promotes mitosis. We determined whether nuclear or cytoplasmic localization of survivin …