Three-Dimensional Cell Culture: A Breakthrough in Vivo

D Antoni, H Burckel, E Josset, G Noel - International journal of molecular …, 2015 - mdpi.com
Cell culture is an important tool for biological research. Two-dimensional cell culture has
been used for some time now, but growing cells in flat layers on plastic surfaces does not …

Effects of bone substitute architecture and surface properties on cell response, angiogenesis, and structure of new bone

FSL Bobbert, AA Zadpoor - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
The success of bone substitutes used to repair bone defects such as critical sized defects
depends on the architecture of the porous biomaterial. The architectural parameters and …

[图书][B] 3D cell culture: a review of current approaches and techniques

JW Haycock - 2011 - Springer
Cell culture in two dimensions has been routinely and diligently undertaken in thousands of
laboratories worldwide for the past four decades. However, the culture of cells in two …

3D printing for the design and fabrication of polymer-based gradient scaffolds

LG Bracaglia, BT Smith, E Watson, N Arumugasaamy… - Acta biomaterialia, 2017 - Elsevier
To accurately mimic the native tissue environment, tissue engineered scaffolds often need to
have a highly controlled and varied display of three-dimensional (3D) architecture and …

Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency

JM Sobral, SG Caridade, RA Sousa, JF Mano, RL Reis - Acta biomaterialia, 2011 - Elsevier
Scaffolds produced by rapid prototyping (RP) techniques have proved their value for tissue
engineering applications, due to their ability to produce predetermined forms and structures …

The role of bioreactors in tissue engineering

I Martin, D Wendt, M Heberer - TRENDS in Biotechnology, 2004 - cell.com
Ex vivo engineering of living tissues is a rapidly developing area with the potential to impact
significantly on a wide-range of biomedical applications. Major obstacles to the generation …

Effects of the architecture of tissue engineering scaffolds on cell seeding and culturing

FPW Melchels, AMC Barradas, CA Van Blitterswijk… - Acta biomaterialia, 2010 - Elsevier
The advance of rapid prototyping techniques has significantly improved control over the
pore network architecture of tissue engineering scaffolds. In this work, we have assessed the …

Effect of fiber diameter, pore size and seeding method on growth of human dermal fibroblasts in electrospun poly (ɛ-caprolactone) fibrous mats

JL Lowery, N Datta, GC Rutledge - Biomaterials, 2010 - Elsevier
Nonwoven fiber mats of poly (ɛ-caprolactone)(PCL) and PCL blended with poly (ethylene
oxide)(PEO) were generated by electrospinning. Differential scanning calorimetry, scanning …

Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes

MW Laschke, Y Harder, M Amon, I Martin… - Tissue …, 2006 - liebertpub.com
Long-term function of three-dimensional (3D) tissue constructs depends on adequate
vascularization after implantation. Accordingly, research in tissue engineering has focused …

Delivery of human fibroblast cells by piezoelectric drop-on-demand inkjet printing

RE Saunders, JE Gough, B Derby - Biomaterials, 2008 - Elsevier
A piezoelectric actuated, drop-on-demand inkjet printing system has been used to deliver
suspensions of human fibroblast cells from a well-characterized cell line (HT 1080) in order …