The use of immune checkpoint inhibitors in oncology and the occurrence of AKI: where do we stand?

R Franzin, GS Netti, F Spadaccino, C Porta… - Frontiers in …, 2020 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are a novel class of immunotherapy drugs that have
improved the treatment of a broad spectrum of cancers as metastatic melanoma, non-small …

[PDF][PDF] Clinical characteristics and treatment of immune-related adverse events of immune checkpoint inhibitors

J Choi, SY Lee - Immune network, 2020 - synapse.koreamed.org
Immune checkpoint inhibitors (ICIs) have been changing the paradigm of cancer treatment.
However, immune-related adverse effects (irAEs) have also increased with the exponential …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

[HTML][HTML] Acute kidney injury in patients treated with immune checkpoint inhibitors

S Gupta, SAP Short, ME Sise, JM Prosek… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI) has
emerged as an important toxicity among patients with cancer. Methods We collected data on …

[HTML][HTML] Immune checkpoint inhibitor nephrotoxicity: what do we know and what should we do?

MA Perazella, AC Shirali - Kidney International, 2020 - Elsevier
Immune checkpoint inhibitors have dramatically improved cancer therapy for many patients.
These humanized monoclonal antibodies against various immune checkpoints (receptors …

Nephrotoxicity of cancer immunotherapies: past, present and future

MA Perazella, AC Shirali - Journal of the American Society of …, 2018 - journals.lww.com
Nephrotoxicity from cancer therapies is common and increasingly encountered in clinical
practice, such that the subfield of “onco-nephrology” has emerged. Conventional …

[HTML][HTML] Immune checkpoint inhibitors and immune-related adverse renal events

SM Herrmann, MA Perazella - Kidney international reports, 2020 - Elsevier
Renal toxicities have been increasingly recognized as complications of the immune
checkpoint inhibitors (ICIs). Recent studies have outlined the incidence and potential risk …

Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury

B Sprangers, DE Leaf, C Porta, MJ Soler… - Nature Reviews …, 2022 - nature.com
Since their introduction into clinical practice a decade ago, immune checkpoint inhibitors
(ICIs) have had an overwhelming impact on cancer treatment. Use of these agents in …

Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline

ES Husebye, F Castinetti, S Criseno… - European journal of …, 2022 - academic.oup.com
Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment but are associated
with significant autoimmune endocrinopathies that pose both diagnostic and treatment …

Renal adverse effects of immune checkpoints inhibitors in clinical practice: ImmuNoTox study

M Espi, C Teuma, E Novel-Catin, D Maillet… - European Journal of …, 2021 - Elsevier
Abstract Background/objectives Acute Kidney Injury (AKI), induced by Checkpoint Inhibitors
therapies (CPI-induced AKI), is an uncommon but severe Immune-Related Adverse Event …