The antibiotic crisis has led to a pressing need for alternatives such as antimicrobial
peptides (AMPs). Recent work has shown that these molecules have great potential not only …

Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …

Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …

As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …

As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …

The pulmonary airways are continuously exposed to bacteria. As a first line of defense
against infection, the airway surface liquid (ASL) contains a complex mixture of antimicrobial …

Oysters are representative bivalve molluscs that are widely distributed in world oceans. As
successful colonizers of estuaries and intertidal zones, oysters are remarkably resilient …

Antimicrobial peptides (AMPs) are anti-infectives that have the potential to be used as a
novel and untapped class of biotherapeutics. Modes of action of antimicrobial peptides …