[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …

RD Kanabalan, LJ Lee, TY Lee, PP Chong… - Microbiological …, 2021 - Elsevier
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Phage engineering and phage‐assisted CRISPR‐Cas delivery to combat multidrug‐resistant pathogens

K Khambhati, G Bhattacharjee, N Gohil… - Bioengineering & …, 2023 - Wiley Online Library
Antibiotic resistance ranks among the top threats to humanity. Due to the frequent use of
antibiotics, society is facing a high prevalence of multidrug resistant pathogens, which have …

Does Mycobacterium tuberculosis var. bovis Survival in the Environment Confound Bovine Tuberculosis Control and Eradication? A Literature Review

AR Allen, T Ford, RA Skuce - Veterinary medicine international, 2021 - Wiley Online Library
Bovine tuberculosis (bTB) is one of the globe's most common, multihost zoonoses and
results in substantial socioeconomic costs for governments, farming industries, and tax …

Mannose-Functionalized Isoniazid-Loaded Nanostructured Lipid Carriers for Pulmonary Delivery: In Vitro Prospects and In Vivo Therapeutic Efficacy Assessment

S Ahalwat, DC Bhatt, S Rohilla, V Jogpal, K Sharma… - Pharmaceuticals, 2023 - mdpi.com
Resistance to isoniazid (INH) is common and increases the possibility of acquiring multidrug-
resistant tuberculosis. For this study, isoniazid-loaded nanostructured lipid carriers (INH …

Human leukocyte antigen (HLA) system: genetics and association with bacterial and viral infections

S Medhasi, N Chantratita - Journal of Immunology Research, 2022 - Wiley Online Library
The human leukocyte antigen (HLA) system is one of the most crucial host factors
influencing disease progression in bacterial and viral infections. This review provides the …

MmpL3 inhibition as a promising approach to develop novel therapies against tuberculosis: a spotlight on SQ109, clinical studies, and patents literature

M Imran, MK Arora, A Chaudhary, SA Khan, M Kamal… - Biomedicines, 2022 - mdpi.com
Tuberculosis (TB) is accountable for considerable global morbidity and mortality. Effective
TB therapy with multiple drugs completes in about six months. The longer duration of TB …

Antimonene, CNT and MoS2 Based SPR-Fiber-Optic Probe for Tuberculosis Detection

B Kaur, S Kumar, BK Kaushik - IEEE Sensors Journal, 2022 - ieeexplore.ieee.org
In this work, two–dimensional (2D) materials-based surface plasmon resonance assisted
fiber sensor is designed to detect the tuberculosis (TB) disease. Transfer matrix method …

Macrophage-targeted nanoparticles mediate synergistic photodynamic therapy and immunotherapy of tuberculosis

N Tian, H Duan, T Cao, G Dai, G Sheng, H Chu… - RSC advances, 2023 - pubs.rsc.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that
poses a serious global public health threat. Due to the high incidence of adverse reactions …

[HTML][HTML] Mtb/HIV co-infection immune microenvironment subpopulations heterogeneity

J Gao, X Huang, Q Zhu, H He, J Zhang, J Chen… - International …, 2024 - Elsevier
Background The co-infection of human immunodeficiency virus type 1 (HIV-1) and
tuberculosis poses a lethal threat. Currently, our understanding of the altered immune …

Emerging extracellular molecular targets for innovative pharmacological approaches to resistant Mtb infection

A Italia, MM Shaik, F Peri - Biomolecules, 2023 - mdpi.com
Emerging pharmacological strategies that target major virulence factors of antibiotic-
resistant Mycobacterium tuberculosis (Mtb) are presented and discussed. This review is …