The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage
The pathophysiological functions of proline-glutamic acid (PE)/proline-proline-glutamic acid
(PPE) family of proteins of Mycobacterium tuberculosis are not well understood. In this study …
(PPE) family of proteins of Mycobacterium tuberculosis are not well understood. In this study …
The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production
Mycobacterium tuberculosis, the bacterium that causes tuberculosis, is one of the most
successful pathogens of humans. It has evolved several adaptive skills and evasion …
successful pathogens of humans. It has evolved several adaptive skills and evasion …
[HTML][HTML] Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression
M Shweash, HA McGachy, J Schroeder… - Molecular …, 2011 - Elsevier
The effects of Leishmania mexicana metacyclic promastigotes upon MAP kinase signalling
in mouse bone marrow macrophages and subsequent expression of the disease regulatory …
in mouse bone marrow macrophages and subsequent expression of the disease regulatory …
An involvement of SR-B1 mediated PI3K–Akt–eNOS signaling in HDL-induced cyclooxygenase 2 expression and prostacyclin production in endothelial cells
QH Zhang, XY Zu, RX Cao, JH Liu, ZC Mo… - Biochemical and …, 2012 - Elsevier
It is well-known that sphingosine-1-phosphate (S1P), the phospholipid content of HDL,
binding to S1P receptors can raise COX-2 expression and PGI2 release through …
binding to S1P receptors can raise COX-2 expression and PGI2 release through …
Glutathione-redox balance regulates c-rel–driven IL-12 production in macrophages: possible implications in Antituberculosis immunotherapy
The glutathione-redox balance, expressed as the ratio of intracellular reduced glutathione
(GSH) and oxidized glutathione, plays an important role in regulating cellular immune …
(GSH) and oxidized glutathione, plays an important role in regulating cellular immune …
Porcine circovirus type 2 suppresses IL-12p40 induction via capsid/gC1qR-mediated microRNAs and signalings
Q Du, X Wu, T Wang, X Yang, Z Wang… - The Journal of …, 2018 - journals.aai.org
Abstract Porcine circovirus (PCV) type 2 (PCV2), an immunosuppression pathogen, is often
found to increase the risk of other pathogenic infections. Yet the relative immune …
found to increase the risk of other pathogenic infections. Yet the relative immune …
New perspectives of nitric oxide donors in cardiac arrest and cardiopulmonary resuscitation treatment
P Kruzliak, O Pechanova, T Kara - Heart Failure Reviews, 2014 - Springer
Nitric oxide (NO) is often used to treat heart failure accompanied with pulmonary edema.
According to present knowledge, however, NO donors are contraindicated when systolic …
According to present knowledge, however, NO donors are contraindicated when systolic …
[PDF][PDF] NF-κB-Inducing Kinase Is Essential for Effective c-Rel Transactivation and Binding to the Il12b Promoter in Macrophages
N Cuesta, AD Staniszewska, C Moreno, C Punzón… - Biology, 2025 - researchgate.net
This study investigates the role of NIK in activating specific inflammatory genes in
macrophages, focusing on the effect of a mutation in NIK found in alymphoplasia (aly/aly) …
macrophages, focusing on the effect of a mutation in NIK found in alymphoplasia (aly/aly) …
Human mesenchymal stem cells: New sojourn of bacterial pathogens
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tuberculosis), is the leading
infectious disease which claims one human life every 15–20 s globally. The persistence of …
infectious disease which claims one human life every 15–20 s globally. The persistence of …
[PDF][PDF] 硝普钠对内毒素诱导的U937 细胞CD14 表达的影响
昊学玲， 赵云峰， 王兴胜， 钱桂生， 陈维中 - 中国急救医学 - cnemergency.org.cn
目的研究硝普钠(SNP) 对内毒素(LPS) 诱导的人单核巨噬细胞株U937 表达CDl4 的影响.
方法佛波脂(PMA) 诱导U937 成熟后分为四组, 即对照组(不给任何药物), LPS 组(10 ng/mL …
方法佛波脂(PMA) 诱导U937 成熟后分为四组, 即对照组(不给任何药物), LPS 组(10 ng/mL …