Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

IA Yang, CR Jenkins, SS Salvi - The Lancet Respiratory Medicine, 2022 - thelancet.com
Chronic obstructive pulmonary disease (COPD) was traditionally thought to be caused by
tobacco smoking. However, recognition of the importance of non-smoking-related risk …

Airway remodeling in asthma

KP Hough, ML Curtiss, TJ Blain, RM Liu, J Trevor… - Frontiers in …, 2020 - frontiersin.org
Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

After asthma: redefining airways diseases

ID Pavord, R Beasley, A Agusti, GP Anderson, E Bel… - The Lancet, 2018 - thelancet.com
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

[HTML][HTML] A summary of the new GINA strategy: a roadmap to asthma control

HK Reddel, ED Bateman, A Becker… - European …, 2015 - publications.ersnet.org
Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and
annually updated a global strategy for asthma management and prevention that has formed …

Managing comorbidities in COPD

G Hillas, F Perlikos, I Tsiligianni… - International journal of …, 2015 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. Age and smoking are common risk factors for COPD and other illnesses, often …

Asthma and COPD overlap syndrome (ACOS): a systematic review and meta analysis

A Alshabanat, Z Zafari, O Albanyan, M Dairi… - PloS one, 2015 - journals.plos.org
Background The combination of asthma and chronic obstructive pulmonary disease
(COPD), or ACOS is a recently defined syndrome. The epidemiology of the condition is …

Increased risk of exacerbation and hospitalization in subjects with an overlap phenotype: COPD-asthma

AMB Menezes, MM de Oca, R Pérez-Padilla… - Chest, 2014 - Elsevier
Background Several COPD phenotypes have been described; the COPD-asthma overlap is
one of the most recognized. The aim of this study was to evaluate the prevalence of three …

Defining the asthma-COPD overlap syndrome in a COPD cohort

BG Cosio, JB Soriano, JL López-Campos… - Chest, 2016 - Elsevier
Background Asthma-COPD overlap syndrome (ACOS) has been recently described by
international guidelines. A stepwise approach to diagnosis using usual features of both …

The overlap syndrome of asthma and COPD: what are its features and how important is it?

PG Gibson, JL Simpson - Thorax, 2009 - thorax.bmj.com
There is a need to re-evaluate the concept of asthma and chronic obstructive pulmonary
disease (COPD) as separate conditions, and to consider situations when they may coexist …

Asthma in older adults

PG Gibson, VM McDonald, GB Marks - The lancet, 2010 - thelancet.com
Asthma in older people is common and is characterised by underdiagnosis and
undertreatment. Ageing is associated with unique issues that modify expression …