Click chemistry strategies for the accelerated synthesis of functional macromolecules

Z Geng, JJ Shin, Y Xi, CJ Hawker - Journal of Polymer Science, 2021 - Wiley Online Library
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …

The dendrimer paradox–high medical expectations but poor clinical translation

S Svenson - Chemical Society Reviews, 2015 - pubs.rsc.org
This review was written with the intention to critically evaluate the status of dendrimers as
drug carriers and find answers as to why this class of compounds has not translated into the …

Recent advances in click chemistry applied to dendrimer synthesis

M Arseneault, C Wafer, JF Morin - Molecules, 2015 - mdpi.com
Dendrimers are monodisperse polymers grown in a fractal manner from a central point. They
are poised to become the cornerstone of nanoscale devices in several fields, ranging from …

Orthogonal multiple click reactions in synthetic polymer chemistry

U Tunca - Journal of Polymer Science Part A: Polymer …, 2014 - Wiley Online Library
This review highlights the concept of multiple click reaction strategy which is utilized for
design and synthesis of well‐defined complex macromolecular structures as well as …

Syntheses and applications of dendronized polymers

X Liu, W Lin, D Astruc, H Gu - Progress in Polymer Science, 2019 - Elsevier
The past several decades have witnessed the rapid development of dendronized polymers
(DPs) and the transformation of the research field into a new area at the interfaces of organic …

Redox-responsive biodegradable dendronized polymers: A side-chain modulation based fabrication of drug delivery vehicles

F Calik, A Degirmenci, R Sanyal, A Sanyal - European Polymer Journal, 2023 - Elsevier
Among various nanomedicine platforms, stimuli-responsive biodegradable polymeric
micelles offer a viable approach to address challenges in cancer therapy. Herein, we report …

Diversity-oriented polymerization: one-shot synthesis of library of graft and dendronized polymers by Cu-catalyzed multicomponent polymerization

H Kim, KT Bang, I Choi, JK Lee… - Journal of the American …, 2016 - ACS Publications
Graft and dendronized polymers have attracted much attention in the polymer community,
and there have been significant efforts to develop better synthetic methods. Herein, we …

Orthogonal synthesis and modification of polymer materials

A Shahrokhinia, P Biswas… - Journal of Polymer …, 2021 - Wiley Online Library
In this review, we detail the progress throughout the years toward developing truly
orthogonal polymerization mechanisms and modification procedures en route to complex …

Ultrafast and efficient aza-and thiol-Michael reactions on a polyester scaffold with internal electron deficient triple bonds

US Gunay, M Cetin, O Daglar, G Hizal, U Tunca… - Polymer …, 2018 - pubs.rsc.org
A polyester scaffold possessing electron deficient triple bonds in the main chain was
prepared and utilized as a precursor for aza-and thiol-Michael addition reactions. A variety …

Click chemistry in macromolecular design: complex architectures from functional polymers

M Arslan, MA Tasdelen - Chemistry Africa, 2019 - Springer
This contribution reviews the applications of click chemistry reactions in design and
synthesis of various macromolecular architectures that hold key aspects in polymer science …