Cascade reactions in total synthesis

KC Nicolaou, DJ Edmonds… - Angewandte Chemie …, 2006 - Wiley Online Library
The design and implementation of cascade reactions is a challenging facet of organic
chemistry, yet one that can impart striking novelty, elegance, and efficiency to synthetic …

Kaskadenreaktionen in der Totalsynthese

KC Nicolaou, DJ Edmonds, PG Bulger - Angewandte Chemie, 2006 - Wiley Online Library
Abstract Die Entwicklung und Umsetzung von Kaskadenreaktionen hat zu beachtlichen
neuartigen, eleganten und effizienten Synthesestrategien geführt. Als besonders …

Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance

KC Nicolaou, CRH Hale, C Nilewski… - Chemical Society …, 2012 - pubs.rsc.org
The advent of organic synthesis and the understanding of the molecule as they occurred in
the nineteenth century and were refined in the twentieth century constitute two of the most …

Synthesis of xanthones: an overview

ME Sousa, MMM Pinto - Current medicinal chemistry, 2005 - ingentaconnect.com
Among the known synthetic routes to obtain xanthones, the Grover, Shah, and Shah
reaction, the cyclodehydration of 2, 2'-dihydroxybenzophenones and electrophilic …

Molecular targets of gambogic acid in cancer: recent trends and advancements

D Kashyap, R Mondal, HS Tuli, G Kumar, AK Sharma - Tumor Biology, 2016 - Springer
Natural compounds have been known as biosafety agents for their significant clinical and
biological activity against dreadful diseases, including cancer, cardiovascular, and …

Chemistry and Biology of the Caged Garcinia Xanthones

O Chantarasriwong, A Batova… - … A European Journal, 2010 - Wiley Online Library
Natural products have been a great source of many small molecule drugs for various
diseases. In spite of recent advances in biochemical engineering and fermentation …

Efficient Construction of Pyrano[3,2‐a]carbazoles: Application to a Biomimetic Total Synthesis of Cyclized Monoterpenoid Pyrano[3,2‐a]carbazole Alkaloids

R Hesse, KK Gruner, O Kataeva… - … A European Journal, 2013 - Wiley Online Library
We have developed a highly efficient route to 2‐hydroxy‐3‐methylcarbazole (1) via a
palladium‐catalyzed construction of the carbazole skeleton. Using 1 as relay compound …

[图书][B] Biomimetic organic synthesis

E Poupon, B Nay - 2011 - books.google.com
In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of
complex natural products is laid out, backed by abundant practical examples from the …

Caged Garcinia xanthones: development since 1937

QB Han, HX Xu - Current medicinal chemistry, 2009 - ingentaconnect.com
Covering: 1937 to Mar 2008. Caged xanthones, characterized by a unique 4-oxa-tricyclo
[4.3. 1.03, 7] dec-2-one scaffold, are a special class of bioactive components mainly derived …

Biomimetic synthesis of antimalarial naphthoquinones

JP Malerich, TJ Maimone, GI Elliott… - Journal of the American …, 2005 - ACS Publications
The total synthesis of naphthoquinone natural products isolated from the Bignoniaceae plant
family is described. Pinnatal, isopinnatal, sterekunthals A and B, pyranokunthones A and B …