Purinergic signalling, ie, the role of nucleotides as extracellular signalling molecules, was
proposed in 1972. However, this concept was not well accepted until the early 1990's when …

Although the urinary bladder urothelium has classically been thought of as a passive barrier
to ions and solutes, a number of novel properties have been recently attributed to urothelial …

The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

There is a brief introductory summary of purinergic signaling involving ATP storage, release,
and ectoenzymatic breakdown, and the current classification of receptor subtypes for …

Purinergic signalling is involved in a number of physiological and pathophysiological
activities in the lower urinary tract. In the bladder of laboratory animals there is …

Pathogenic bacteria use various strategies to interact with the host organisms. Among them,
toxin production constitutes an efficient way to alter specific functions of target cells. Various …

There is a brief summary of the background literature about purinergic signalling. The review
then considers purinergic mechanosensory transduction involved in visceral, cutaneous and …

There is a brief summary of the early background literature about purinergic signalling and
its involvement in pain, of ATP storage, release and ectoenzymatic breakdown and of the …

Non-neuronal release of acetylcholine (ACh) has been proposed to play a role in urinary
bladder function. These studies investigated the expression and function of the non …

The internal face of the detrusor smooth muscle wall of the urinary bladder is covered by a
mucosa, separating muscle from the hostile environment of urine. However, the mucosa is …