Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Although systemic hypertension affects a large proportion of the population, its etiology
remains poorly defined. Emerging evidence supports the concept that immune cells become …

Immune mechanisms have been recognized to have a role in the pathogenesis of
hypertension, vascular disease and kidney damage in humans and animals for many …

Hypertension is an important risk factor for cardiovascular morbidity and mortality and for
events such as myocardial infarction, stroke, heart failure and chronic kidney disease and is …

Abstract Purpose of Review To summarize key advances in our understanding of the role of
interleukin 17A (IL-17A) in the pathogenesis of hypertension and highlight important areas …

It is well accepted that the immune system and some cells from adaptive and innate
immunity are necessary for the initiation/perpetuation of arterial hypertension (AH) …

Evidence for the increased risk of cardiovascular morbidity and mortality in patients with
chronic inflammatory and systemic autoimmune diseases has accumulated during the past …

Traditionally, arterial hypertension and subsequent end‐organ damage have been
attributed to haemodynamic factors, but increasing evidence indicates that inflammation also …

Oxidative stress and renal inflammation play a pivotal role in the pathogenesis of
hypertension. The redox-sensitive transcription factor, nuclear factor E2-related factor 2 …

Metabolic diseases, such as diabetes, gout and hyperlipidemia are global health
challenges. Among them, diabetes has been extensively investigated. Type 2 diabetes …