In regenerative medicine, adult stem cells are the most promising cell types for cell-based
therapies. As a new source for multipotent stem cells, human adipose tissue has been …

Millions of Americans suffer from skeletal muscle injuries annually that can result in
volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss …

Aims Adipose-derived regenerative cells (ADRCs) can be isolated from liposuction aspirates
and prepared as fresh cells for immediate administration in cell therapy. We performed the …

Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

Ischemic diseases, the leading cause of disability and death, are caused by the stenosis or
obstruction of arterioles/capillaries that is not compensated for by vessel dilatation or …

Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …

Skeletal muscle tissue is characterized by high metabolic requirements, defined structure
and high regenerative potential. As such, it constitutes an appealing platform for tissue …

Neovascularization and angiogenesis are vital processes in the repair of damaged tissue,
creating new blood vessel networks and increasing oxygen and nutrient supply for …

Tissue regeneration is impaired in aged individuals. Adipose-derived mesenchymal stromal
cells (ADSCs), a promising source for cell therapy, were shown to secrete various …

Ischemic diseases such as myocardial infarction, ischemic stroke, and critical limb ischemia
are immense public health challenges. Current pharmacotherapy and surgical approaches …