The most significant advance in the medical management of HIV-1 infection has been the
treatment of patients with antiviral drugs, which can suppress HIV-1 replication to …

The early immune response to HIV-1 infection is likely to be an important factor in
determining the clinical course of disease. Recent data indicate that the HIV-1 quasispecies …

Chronic activation of the immune system is a hallmark of progressive HIV infection and
better predicts disease outcome than plasma viral load, yet its etiology remains obscure …

The AIDS pandemic continues to present us with unique scientific and public health
challenges. Although the development of effective antiretroviral therapy has been a major …

There is an intense interplay between HIV and the immune system, and the literature is
replete with studies describing various immunological phenomena associated with HIV …

Measures to prevent sexual mucosal transmission of human immunodeficiency virus (HIV)-1
are urgently needed to curb the growth of the acquired immunodeficiency syndrome (AIDS) …

A mainstay of strategies to prevent HIV-1 transmission is to use antiretroviral therapy (ART)
for pre-exposure prophylaxis (PrEP). Critical to the design and interpretation of PrEP …

Abstract Human immunodeficiency virus-1 (HIV-1) is primarily transmitted sexually. Dendritic
cells (DCs) in the subepithelium transmit HIV-1 to T cells through the C-type lectin DC …

There has recently been a resurgence of interest in the gastrointestinal pathology observed
in patients infected with HIV. The gastrointestinal tract is a major site of HIV replication …

Vaginal instillation of small-interfering RNA (siRNA) using liposomes has led to silencing of
endogenous genes in the genital tract and protection against challenge from infectious …