Abstract Systems neuroscience approaches with a focus on large-scale brain organization
and network analysis are advancing foundational knowledge of how cognitive control …

The ability to sustain internal representations of the sensory environment beyond immediate
perception is a fundamental requirement of cognitive processing. In recent years, debates …

When experts are immersed in a task, do their brains prioritize task-related activity? Most
efforts to understand neural activity during well-learned tasks focus on cognitive …

Neural activity throughout the cortex is correlated with perceptual decisions, but inactivation
studies suggest that only a small number of areas are necessary for these behaviors. Here …

When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrouping between attempts. It is …

Calcium imaging with fluorescent protein sensors is widely used to record activity in
neuronal populations. The transform between neural activity and calcium-related …

Perceptual choices depend not only on the current sensory input but also on the behavioral
context, such as the history of one's own choices. Yet, it remains unknown how such history …

Computational analysis of cellular activity has developed largely independently of modern
transcriptomic cell typology, but integrating these approaches may be essential for full …

Working memory involves the short-term maintenance of information and is critical in many
tasks. The neural circuit dynamics underlying working memory remain poorly understood …

Widefield imaging of calcium dynamics is an emerging method for mapping regional neural
activity but is currently limited to restrained animals. Here we describe cScope, a head …