Respiratory syncytial virus: infection, detection, and new options for prevention and treatment

C Griffiths, SJ Drews, DJ Marchant - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum

JK Baird - 1998 - digitalcommons.unl.edu
Naturally acquired immunity to Plasmodium falciparum may be linked to key features of the
immune system that change during normal development and ageing. Evidence of this was …

The role of T helper cells in neuroprotection and regeneration

S Hendrix, R Nitsch - Journal of neuroimmunology, 2007 - Elsevier
The inflammatory wound healing response of the central nervous system (CNS) following
mechanical injury is characterized by at least one or two phases of T cell infiltration …

[HTML][HTML] Aging and T-cell-mediated immunity

B Chakravarti, GN Abraham - Mechanisms of ageing and development, 1999 - Elsevier
Changes in the T-lymphocyte compartment represent the most critical component of
immunological aging. Recent studies have demonstrated that the age-related decline in T …

The immune S ystem in the elderly: II. Specific Cellular Immunity

L Ginaldi, MD Martinis, A D'ostilio, L Marini… - Immunologic …, 1999 - Springer
Numerous changes occur in the immune system with advancing age, probably contributing
to the decreased immunoresponsiveness in the elderly. These changes are often associated …

Zinc, metallothioneins, immune responses, survival andageing

E Mocchegiani, M Muzzioli, R Giacconi - Biogerontology, 2000 - Springer
Zinc is required as a catalytic, structural (zincfingers) and regulatory ion. In this capacity, it
isinvolved in many homeostatic mechanisms, includingimmune responses. Metallothioneins …

Hematopoiesis and cytokines: relevance to cancer and aging

CA Baraldi-Junkins, AC Beck, G Rothstein - Hematology/oncology clinics of …, 2000 - Elsevier
Although an array of physiologic alterations occur in older persons, the fundamental
mechanisms that account for these changes are not well understood. Changes such as …

Leukocyte function and life span in a murine model of premature immunosenescence

N Guayerbas, M Puerto, VM Vıctor, J Miquel… - Experimental …, 2002 - Elsevier
Aging associates with a decline of physiological functions, including the function of the
nervous and the immune system. These aged-related changes occur in various degrees in …

Zinc, infections and immunosenescence

E Mocchegiani, R Giacconi, M Muzzioli… - Mechanisms of ageing …, 2001 - Elsevier
Infections may cause mortality in old age due to damaged immune responses. As zinc is
required as a catalyst, structural (zinc fingers) and regulatory ion, it is involved in many …

Immunological changes in the elderly

L Ginaldi, M De Martinis, A D'ostilio, L Marini… - Aging Clinical and …, 1999 - Springer
Immunosenescence is a complex remodelling of the immune system which may contribute
significantly to morbidity and mortality in the elderly. Much evidence suggests an association …