Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

Primary biliary cholangitis: Epidemiology, prognosis, and treatment

J Trivella, BV John, C Levy - Hepatology communications, 2023 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease
characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the …

Hepatic immune regulation and sex disparities

P Burra, A Zanetto, B Schnabl, T Reiberger… - Nature Reviews …, 2024 - nature.com
Chronic liver disease is a major cause of morbidity and mortality worldwide. Epidemiology,
clinical phenotype and response to therapies for gastrointestinal and liver diseases are …

Optimizing therapy in primary biliary cholangitis: alkaline phosphatase at six months identifies one‐year non‐responders and predicts survival

CF Murillo Perez, S Ioannou, I Hassanally… - Liver …, 2023 - Wiley Online Library
Abstract Background and Aims Patients with primary biliary cholangitis (PBC) and
insufficient response to ursodeoxycholic acid (UDCA), currently assessed after 1 year, are …

Contemporary epidemiology of primary biliary cholangitis

F Colapietro, A Bertazzoni, A Lleo - Clinics in Liver Disease, 2022 - liver.theclinics.com
Primary biliary cholangitis (PBC) is an immune-mediated cholestatic liver disease mainly
diagnosed in middle-aged women, with a female-to-male ratio between 4 to 5: 1 and 9 to 10 …

Linking Human Betaretrovirus with autoimmunity and liver disease in patients with primary biliary cholangitis

H Syed, T Penner, AL Mason - Viruses, 2022 - mdpi.com
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by the
production of diagnostic antimitochondrial antibodies (AMA) reactive to the pyruvate …

Primary Biliary Cholangitis: Personalizing Second-Line Therapies-R1

C Levy, CL Bowlus - Hepatology, 2024 - journals.lww.com
Primary biliary cholangitis (PBC) is an enigmatic, autoimmune disease targeting the small
intralobular bile ducts resulting in cholestasis and potentially progression to biliary cirrhosis …

Causal associations between systemic lupus erythematosus and primary biliary cholangitis: A bidirectional Mendelian randomization study

M Zhong, H An, H Gan - Heliyon, 2024 - cell.com
Objectives The association between systemic lupus erythematosus (SLE) and primary biliary
cholangitis (PBC) has been increasingly recognized. However, the existence of causal …

“My feelings and my thoughts are my lived experience, not the numbers they show me on a piece of paper”: Indigenous experiences of liver transplantation in British …

C Cassidy-Matthews, M Pearce, T Hussaini… - … of Circumpolar Health, 2024 - Taylor & Francis
ABSTRACT Indigenous Peoples in Canada face healthcare inequities impacting access to
solid organ transplantation. The experiences of Indigenous patients during the liver …

Epidemiological trends and outcomes of primary biliary cholangitis in South Korea between 2009 and 2019

KA Kim, HY Choi, M Ki, ES Jang, SH Jeong - Journal of Gastroenterology, 2023 - Springer
Background There are no longitudinal studies on the epidemiology of primary biliary
cholangitis (PBC) in Korea. This study aimed to elucidate the temporal trends in the …