[HTML][HTML] Microneedles for enhanced topical treatment of skin disorders: applications, challenges, and prospects

T Peng, Y Chen, W Hu, Y Huang, M Zhang, C Lu… - Engineering, 2023 - Elsevier
Microneedles (MNs) can be used for the topical treatment of skin disorders as they directly
deliver therapeutics to the site of skin lesions, resulting in increased therapeutic efficacy …

Multiple bacteria recognition mechanisms and their applications

X Yin, J Shan, L Dou, Y Cheng, S Liu… - Coordination Chemistry …, 2024 - Elsevier
Throughout human history, inexhaustible emerging or re-emerging pathogenic bacteria
have never ceased to pose significant challenges to global public health. As the other side …

Dissolving microneedle system containing Ag nanoparticle-decorated silk fibroin microspheres and antibiotics for synergistic therapy of bacterial biofilm infection

Y Li, JY Gong, P Wang, H Fu, F Yousef, R Xie… - Journal of Colloid and …, 2024 - Elsevier
Most cases of delayed wound healing are associated with bacterial biofilm infections due to
high antibiotic resistance. To improve patient compliance and recovery rates, it is critical to …

Nanomedicines for targeted pulmonary delivery: receptor-mediated strategy and alternatives

W Wang, Z Zhong, Z Huang, TN Hiew, Y Huang, C Wu… - Nanoscale, 2024 - pubs.rsc.org
Pulmonary drug delivery of nanomedicines is promising for the treatment of lung diseases;
however, their lack of specificity required for targeted delivery limit their applications …

Epsilon-poly-l-lysine microneedle patch loaded with amorphous doxycycline nanoparticles for synergistic treatment of skin infection

R Luo, D Xian, F Li, G Zhou, L Jiang, J Wu, L Lin… - International Journal of …, 2024 - Elsevier
The development of antibiotic-loaded microneedles has been hindered for years by limited
excipient options, restricted drug-loading space, poor microneedle formability, and short …

[HTML][HTML] Roles of Two-Dimensional Materials in Antibiofilm Applications: Recent Developments and Prospects

L Xin, H Zhao, M Peng, Y Zhu - Pharmaceuticals, 2024 - mdpi.com
Biofilm-associated infections pose a significant challenge in healthcare, constituting 80% of
bacterial infections and often leading to persistent, chronic conditions. Conventional …

Tailoring Vanadium-Based Magnetic Catalyst by In Situ Encapsulation of Tungsten Disulfide and Applications in Abatement of Multiple Pollutants

S Manzoor, K Aziz, H Raza, S Manzoor, MI Khan… - ACS …, 2023 - ACS Publications
A magnetic nanocomposite of tungsten and vanadium was employed as a catalyst for the
mitigation of water contaminants, including a carcinogenic dye (Congo red, CR), a widely …

Copper‐Cysteine Nanostructures for Synergetic Photothermal Therapy and Chemodynamic Therapy of Bacterial Skin Abscesses

H Bagheri, S Bochani, M Seyedhamzeh… - Advanced …, 2024 - Wiley Online Library
Skin lesions, including skin bacterial abscesses, have become one of the most important
health challenges and usually need systemic high‐dose antibiotics. Therefore, it is of …

Biocontrol Microneedle Patch: A Promising Agent for Protecting Citrus Fruits from Postharvest Infection

L Jiang, H Huang, X Shi, J Wu, J Ye, Q Xu, S Fang… - Pharmaceutics, 2023 - mdpi.com
With increasing human awareness of food safety, the replacement of highly toxic pesticides
with biocompatible antimicrobials has become a trend. This study proposes a biocontrol …

Emerging Trends in Dissolving-Microneedle Technology for Antimicrobial Skin-Infection Therapies

R Luo, H Xu, Q Lin, J Chi, T Liu, B Jin, J Ou, Z Xu… - Pharmaceutics, 2024 - mdpi.com
Skin and soft-tissue infections require significant consideration because of their prolonged
treatment duration and propensity to rapidly progress, resulting in severe complications. The …