It has been more than 50 years since the elucidation of the structure of double-helical DNA.
Despite active research and progress in DNA biology and biochemistry, much remains to be …

Understanding how chromatin is spatially and dynamically organized in the nucleus of
eukaryotic cells and how this affects genome functions is one of the main challenges of cell …

The scaling of the average gyration radius of polymers as a function of their length can be
experimen<? format?> tally determined from ensemble measurements, such as light …

DNA bending plays an important role in many biological processes, but its molecular and
energetic details as a function of base sequence remain to be fully understood. Using a …

While the widespread emergence of nanoscience and nanotechnology can be dated back to
the early eighties, the last decade has witnessed a true coming of age of this research field …

The structural flexibility of nucleic acids plays a key role in many fundamental life processes,
such as gene replication and expression, DNA-protein recognition, and gene regulation. To …

Despite the negative charge of the DNA backbone, acidic residues (Asp/Glu) commonly
participate in the base readout, with a strong preference for cytosine. In fact, in the solved …

Because of RNA's ability to encode structure and functional information, researchers have
fabricated diverse geometric structures from this polymer at the micro-and nanoscale. With …

The rotational and translational positioning of nucleosomes on DNA is dependent to a
significant extent on the physicochemical properties of the double helix. We have …

We elaborate on a mean-field extension of the wormlike chain model that accounts for the
presence of long-range correlations (LRC) in the intrinsic curvature disorder of genomic …