The cerebral vascular system services the constant demand for energy during neuronal
activity in the brain. Attempts to delineate the logic of neurovascular coupling have been …

Deciphering neurologic function is a daunting task, requiring understanding the neuronal
networks and emergent properties that arise from the interactions among single neurons …

Flow of cerebrospinal fluid (CSF) through perivascular spaces (PVSs) in the brain is
important for clearance of metabolic waste. Arterial pulsations are thought to drive flow, but …

The majority of the brain's vasculature is composed of intricate capillary networks lined by
capillary pericytes. However, it remains unclear whether capillary pericytes influence blood …

CSF from the subarachnoid space moves rapidly into the brain along paravascular routes
surrounding penetrating cerebral arteries, exchanging with brain interstitial fluid (ISF) and …

Resting-state signals in blood-oxygenation-level-dependent (BOLD) imaging are used to
parcellate brain regions and define" functional connections" between regions. Yet a …

The blood–brain barrier (BBB) is highly selective and acts as the interface between the
central nervous system and circulation. While the BBB is critical for maintaining brain …

Cranial window implants in head-fixed rodents are becoming a preparation of choice for
stable optical access to large areas of the cortex over extended periods of time. Here we …

Cerebrovascular abnormalities have emerged as a preclinical manifestation of Alzheimer's
disease and frontotemporal dementia, diseases characterized by the accumulation of …

Active nerve cells release vasodilators that increase their energy supply by dilating local
blood vessels, a mechanism termed neurovascular coupling and the basis of BOLD …