Increasing the frequency of omicron variant mutations boosts the immune response and may reduce the virus virulence

AA Dawood - Microbial Pathogenesis, 2022 - Elsevier
The coronavirus has posed a serious threat to the world since its discovery in Wuhan in
2019. Beta, gamma, delta, and the final omicron variants have emerged as a result of …

Immunoinformatic prediction of potential immunodominant epitopes from cagW in order to investigate protection against Helicobacter pylori infection based on …

M Chehelgerdi, F Heidarnia, FB Dehkordi… - Functional & Integrative …, 2023 - Springer
Helicobacter pylori is a leading cause of stomach cancer and peptic ulcers. Thus, identifying
epitopes in H. pylori antigens is important for disease etiology, immunological surveillance …

Compatibility of the Ligand Binding Sites in the Spike Glycoprotein of COVID-19 with those in the Aminopeptidase and the Caveolins 1, 2 Proteins

AA Dawood, MA Altobje… - Research Journal of …, 2021 - indianjournals.com
A novel severe viral pneumonia emerged in Wuhan city, China, in December 2019. The
spike glycoprotein of the SARS-CoV-2 plays a crucial role in the viral entry to the host cell …

[PDF][PDF] Molecular docking of SARS-CoV-2 nucleocapsid protein with angiotensin-converting enzyme II

A Dawood, M Altobje, Z Alrassam - Mikrobio Zhu, 2021 - researchgate.net
SARS-CoV-2 remains life-threatening human pathogen witnessed in the present world.
Purpose. The key objective of this research was to incorporate a bioinformatics technique to …

Influence of SARS-CoV-2 variants' spike glycoprotein and RNA-dependent RNA polymerase (nsp12) mutations on remdesivir docking residues

A Dawood - Med Immuno Rus, 2022 - elibrary.ru
Rapid emergence and evolution of novel SARS-CoV-2 variants has raised concerns about
their potential impact on efficiency of currently available vaccines. Among the most …

Implementation of immuno-chemoinformatics approaches to construct multi-epitope for vaccine development against Omicron and Delta SARS-CoV-2 variants

AA Dawood - Vacunas (English Edition), 2022 - Elsevier
Background The new coronavirus is still a life-threatening menace, because of its changing
nature and capacity to produce many mutations to bypass the immune system. The …

[HTML][HTML] Identification of surface glycoprotein mutations of SARS-CoV-2 in isolated strains from Iraq

BI Jasim - Медицинская иммунология, 2022 - cyberleninka.ru
Background: The global pandemic of coronavirus disease is a societal, economic, and
publichealth crisis that is still underway. The spike glycoprotein of SARS-CoV-2 is one of the …

Влияние мутационных вариантов спайкового гликопротеина и РНК-зависимой РНКполимеразы (nsp12) SARS-CoV-2 на участки стыковки с ремдесивиром

АА Давуд - Медицинская иммунология, 2022 - mimmun.ru
Аннотация В связи с быстрым развитием и эволюцией новых вариантов SARS-CoV-2
возникли проблемы, касающиеся их потенциального влияния на эффективность …

Идентификация мутаций поверхностного гликопротеина SARS-CoV-2 в штаммах, изолированных в Ираке

АА Давуд, БИ Ясим… - Медицинская …, 2022 - mimmun.ru
Аннотация Глобальная пандемия коронавирусной инфекции стала длительной
кризисной ситуацией для общества, экономики и здравоохранения, которая …

Simulate the agarose gel of the receptor binding domain in Omicron's spike protein inserted into the pGEM®-T Easy vector using SpeI and SacI restriction enzymes

AA Dawood - … Journal of Computational Biology and Drug …, 2023 - inderscienceonline.com
The Omicron variant of SARS-CoV-2 spreads swiftly among humans because of the
mutations it carries. Aim: The goal of this study was to find a full design of the polymerase …