Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one
of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have …

Hypoxia is a persistent physiological feature of many different solid tumors and a key driver
of malignancy, and in recent years, it has been recognized as an important target for cancer …

Optical-resolution photoacoustic microscopy (OR-PAM) has been developed for anatomical,
functional, and molecular imaging but usually requires multiple scanning for different …

History, presence, and future of mitomycin C in glaucoma fil... : Current Opinion in
Ophthalmology History, presence, and future of mitomycin C in glaucoma filtration surgery …

While it is widely accepted that high intratumoral heterogeneity confers serious challenges
in the emerging resistance and the subsequent effective therapeutic targeting of cancer, the …

Hypoxia is a distinctive feature of most solid tumors due to insufficient oxygen supply of the
abnormal vasculature, which cannot work with the demands of the fast proliferation of cancer …

Hyperbaric oxygen therapy (HBOT) is effective for the medical treatment of diverse diseases,
infections, and tissue injury. In fact, in recent years there is growing evidence on the …

Hypoxia is a serious obstacle in cancer treatment. The aberrant vascular network as well as
the abnormal extracellular matrix arrangement results in formation of a hypoxic regions in …

Doxorubicin (DOX) is a first-line chemo drug for cancer therapy, yet it fails to treat multi-drug-
resistant tumors. Hypoxia is a major causative factor leading to chemotherapy failure …

Multidrug resistance (MDR) in cancer remains a critical obstacle for efficient chemotherapy.
Many MDR reversal agents have been discovered but failed in clinical trials due to severe …