Advances in flavor peptides with sodium-reducing ability: A review

T Gao, X Huang, X Chen, X Cai, J Huang… - Critical reviews in …, 2024 - Taylor & Francis
Condiments (such as sodium chloride and glutamate sodium) cause consumers to ingest
too much sodium and may lead to a variety of diseases, thus decreasing their quality of life …

The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors

L Zhang, JI Mobbs, LT May, A Glukhova… - Current Opinion in …, 2023 - Elsevier
G-protein coupled receptors (GPCRs) are important therapeutic targets for the treatment of
human disease. Although GPCRs are highly successful drug targets, there are many …

Glutathione-Based Photoaffinity Probe Identifies Caffeine as a Positive Allosteric Modulator of the Calcium-Sensing Receptor

NNJ Matarage Don, R Padmavathi… - ACS Chemical …, 2024 - ACS Publications
The calcium-sensing receptor (CaSR), abundantly expressed in the parathyroid gland and
kidney, plays a central role in calcium homeostasis. In addition, CaSR exerts multimodal …

Topical therapy with negative allosteric modulators of the calcium-sensing receptor (calcilytics) for the management of asthma: the beginning of a new era?

D Riccardi, JPT Ward, PL Yarova… - European …, 2022 - Eur Respiratory Soc
In this review article we present the evidence to date supporting the role of the calcium-
sensing receptor (CaSR) as a key, pluripotential molecular trigger for asthma and speculate …

Solid-phase extraction with the functionalization of calcium-sensing receptors onto magnetic microspheres as an affinity probe can capture ligands selectively from …

P Cheng, K Meng, X Shi, M Jiao, Y Han, X Li, P Liu… - Microchimica Acta, 2024 - Springer
Magnetic solid phase extraction with the functionalization of protein onto micro-or nano-
particles as a probe is favorable for the discovery of new drugs from complicated natural …

Recent advances in calcium-sensing receptor structures and signaling pathways

CM Gorvin - Progress in Molecular Biology and Translational …, 2023 - Elsevier
The calcium-sensing receptor (CaSR) is a class C GPCR that has a fundamental role in
extracellular calcium homeostasis by regulating parathyroid hormone release and urinary …

Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively Label Calcium Sensing Receptors In Vitro, In Vivo, and Ex Vivo

D Bátora, JP Fischer, RM Kaderli, M Varga… - ACS pharmacology & …, 2024 - ACS Publications
The calcium sensing receptor (CaSR) is a ubiquitously expressed G-protein coupled
receptor (GPCR) that regulates extracellular calcium signals via the parathyroid glands …

Calcium‐sensing receptor regulates the angiogenic differentiation of LPS‐treated human dental pulp cells via the phosphoinositide 3‐kinase/Akt pathway in vitro

T Yang, P Liu, Z Qiu, Y Zhang… - International Endodontic …, 2024 - Wiley Online Library
Aim The purpose of this study was to investigate the role of calcium‐sensing receptor
(CaSR) in the angiogenic differentiation of lipopolysaccharide (LPS)‐treated human dental …

[图书][B] Hormones

G Litwack - 2022 - books.google.com
Hormones, Fourth Edition provides a report on the field of human hormones viewed in light
of our current understanding of cellular and subcellular architecture, along with the …

Low molecular weight hyaluronan inhibits lung epithelial ion channels by activating the calcium-sensing receptor

A Lazrak, W Song, Z Yu, S Zhang, A Nellore… - Matrix Biology, 2023 - Elsevier
Herein, we tested the hypothesis that low molecular weight hyaluronan (LMW-HA) inhibits
lung epithelial ions transport in-vivo, ex-vivo, and in-vitro by activating the calcium-sensing …