Engineering and monitoring cellular barrier models

J Yeste, X Illa, M Alvarez, R Villa - Journal of biological engineering, 2018 - Springer
Epithelia and endothelia delineate tissue compartments and control their environments by
regulating the passage of ions and solutes. This barrier function is essential for the …

A review of electrical impedance characterization of cells for label-free and real-time assays

HT Ngoc Le, J Kim, J Park, S Cho - BioChip Journal, 2019 - Springer
The aim of this review is to discuss label-free and real-time assays characterizing the
electrical impedance of cells for biomedical and pharmacological applications. Electrical …

Polypyrrole/sulfonated multi-walled carbon nanotubes conductive hydrogel for electrochemical sensing of living cells

M Yang, X Ren, T Yang, C Xu, Y Ye, Z Sun… - Chemical Engineering …, 2021 - Elsevier
Conductive hydrogels, a class of novel polymeric material that combine the electronic
conductivity of intrinsically conductive materials and diverse functionalities of hydrogels, are …

Enzyme-triggered formation of enzyme-tyramine concatamers on nanogold-functionalized dendrimer for impedimetric detection of Hg (II) with sensitivity enhancement

Z Qiu, D Tang, J Shu, G Chen, D Tang - Biosensors and Bioelectronics, 2016 - Elsevier
A new impedimetric sensing strategy based on enzyme-triggered formation of enzyme-
tyramine concatamers on the nanogold-functionalized poly (amidoamine)(PAMAM) …

Impedance-based cellular assays for regenerative medicine

W Gamal, H Wu, I Underwood, J Jia… - … of the Royal …, 2018 - royalsocietypublishing.org
Therapies based on regenerative techniques have the potential to radically improve
healthcare in the coming years. As a result, there is an emerging need for non-destructive …

Blue-light induced breakdown of barrier function on human retinal epithelial cells is mediated by PKC-ζ over-activation and oxidative stress

EK Ozkaya, G Anderson, B Dhillon… - Experimental eye …, 2019 - Elsevier
We aimed to study the time course decrease of human retinal pigment epithelium (RPE)
barrier function when exposed to blue light. To this end, we cultured ARPE-19 cells on …

Real-time monitoring of skin wound healing on nano-grooves topography using electric cell-substrate impedance sensing (ECIS)

Y Cui, Y An, T Jin, F Zhang, P He - Sensors and Actuators B: Chemical, 2017 - Elsevier
Skin wound healing represents a critical medical topic. For its ideal case, the injured tissue
can repair quickly without scars. In this paper, an ECIS device was developed using nano …

[HTML][HTML] Label-free technology and patient cells: from early drug development to precision medicine

JM Hillger, WL Lieuw, LH Heitman, AP IJzerman - Drug discovery today, 2017 - Elsevier
Highlights•Label-free assays increase biorelevance over traditional label-based
studies.•Patient-derived cells offer increased physiological representability.•Impedance …

A micro EIT sensor for real-time and non-destructive 3-D cultivated cell imaging

X Yin, H Wu, J Jia, Y Yang - IEEE Sensors Journal, 2018 - ieeexplore.ieee.org
A micro electrical impedance tomography (EIT) sensor with radially distributed planar
electrodes was designed, characterized, and experimentally validated for real-time and non …

Effects of electrode diameter on the detection sensitivity and frequency characteristics of electric cell-substrate impedance sensing

YT Lai, YS Chu, JC Lo, YH Hung, CM Lo - Sensors and Actuators B …, 2019 - Elsevier
Cell-based electrochemical impedance spectroscopy (EIS) has emerged as a label-free
approach to monitor whole cellular behavior in response to the environmental stimuli in real …