The Alzheimer's disease assessment scale–cognitive subscale (ADAS-Cog): modifications and responsiveness in pre-dementia populations. a narrative review

JK Kueper, M Speechley… - Journal of Alzheimer's …, 2018 - content.iospress.com
Abstract The Alzheimer's Disease Assessment Scale–Cognitive Subscale (ADAS-Cog) was
developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease …

Get a grip: individual variations in grip strength are a marker of brain health

RG Carson - Neurobiology of aging, 2018 - Elsevier
Demonstrations that grip strength has predictive power in relation to a range of health
conditions—even when these are assessed decades later—has motivated claims that hand …

Handgrip strength as a means of monitoring progression of cognitive decline–a scoping review

NE Fritz, CJ McCarthy, DE Adamo - Ageing research reviews, 2017 - Elsevier
Cognitive decline in older adults contributes to reduced ability to perform daily tasks and
continued disuse leads to muscle weakness and potentiates functional loss. Despite explicit …

Frailty as a predictor of cognitive disorders: a systematic review and meta-analysis

MK Borges, M Canevelli, M Cesari… - Frontiers in medicine, 2019 - frontiersin.org
Background/Aim: Current evidence in the literature supports associations between frailty,
cognitive impairment, and dementia. The study aim was to describe the risk of cognitive …

How gait influences frailty models and health‐related outcomes in clinical‐based and population‐based studies: a systematic review

I Bortone, R Sardone, L Lampignano… - Journal of cachexia …, 2021 - Wiley Online Library
Aging is often associated with a decline in physical function that eventually leads to loss of
autonomy in activities of daily living (ADL). Walking is a very common ADL, important for …

Cognitive frailty: a systematic review of epidemiological and neurobiological evidence of an age-related clinical condition

F Panza, V Solfrizzi, MR Barulli, A Santamato… - Rejuvenation …, 2015 - liebertpub.com
Advancing age is the focus of recent studies on familial and sporadic Alzheimer's disease
(AD), suggesting a prolonged pre-clinical phase several decades before the onset of …

Handgrip strength values of Portuguese older adults: a population based study

J Mendes, TF Amaral, N Borges, A Santos, P Padrão… - BMC geriatrics, 2017 - Springer
Background Handgrip strength is used to identify sarcopenia and frailty phenotypes, being a
potential predictor of mortality in older adults. However, uniformity is lacking in the reference …

Frailty and cognitive decline: how do they relate?

M Canevelli, M Cesari, GA van Kan - Current Opinion in Clinical …, 2015 - journals.lww.com
The present findings are suggestive of an almost complete lack of evidence on the
addressed topic. In particular, randomized controlled trials are strongly needed in order to …

Targeting cognitive frailty: clinical and neurobiological roadmap for a single complex phenotype

F Panza, D Seripa, V Solfrizzi, R Tortelli… - Journal of …, 2015 - content.iospress.com
Late-life cognitive disorders may be prevented by influencing age-related conditions such as
frailty, characterized by decreased resistance to stressors and increased risk for adverse …

Cognitive reserve and Alzheimer's disease

W Xu, JT Yu, MS Tan, L Tan - Molecular neurobiology, 2015 - Springer
Abstract Alzheimer's disease (AD), as a neurodegenerative process caused by widespread
senile plaques and neurofibrillary tangles, is faced with an increasingly higher incidence as …