Anticancer potential of furanocoumarins: mechanistic and therapeutic aspects

S Ahmed, H Khan, M Aschner, H Mirzae… - International Journal of …, 2020 - mdpi.com
Cancer is one of the most extreme medical conditions in both developing and developed
countries around the world, causing millions of deaths each year. Chemotherapy and/or …

Coumarin-based derivatives with potential anti-HIV activity

Z Xu, Q Chen, Y Zhang, C Liang - Fitoterapia, 2021 - Elsevier
Acquired immunodeficiency syndrome (AIDS), as a result of human immunodeficiency virus
(HIV) infection which leads to severe suppression of immune functions, is an enormous …

A review on pharmacological properties of coumarins

D Srikrishna, C Godugu… - Mini reviews in medicinal …, 2018 - ingentaconnect.com
The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural
products, displays diverse pharmacological properties. It has attracted the attention of …

Coumarin compounds in medicinal chemistry: some important examples from the last years

TM Pereira, DP Franco, F Vitorio… - Current topics in …, 2018 - ingentaconnect.com
Coumarins are natural products characterized as 1, 2 benzopyrones widely distributed in
plants, as well as, in many species of fungi and bacteria. Nowadays, many synthetic …

[HTML][HTML] Pharmacological perspectives and molecular mechanisms of coumarin derivatives against virus disease

Z Li, D Kong, Y Liu, M Li - Genes & Diseases, 2022 - Elsevier
Infections caused by virus are one of the foremost causes of morbidity and mortality in the
world. Although a number of antiviral drugs are currently used for treatment of various kinds …

Natural and synthetic coumarins as potential anticancer agents

J Klenkar, M Molnar - Journal of chemical and pharmaceutical research, 2015 - croris.hr
Sažetak Coumarins, natural or synthetic, due to their wide range of biological activities, have
become an interesting subject of investigation for many researchers. Coumarin scaffold has …

6, 7-Coumarin-heterocyclic hybrids: a comprehensive review of their natural sources, synthetic approaches, and bioactivity

NM Zeki, YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

A Method for LC-MS/MS Profiling of Coumarins in Zanthoxylum zanthoxyloides (Lam.) B. Zepernich and Timler Extracts and Essential Oils

Y Tine, F Renucci, J Costa, A Wélé, J Paolini - Molecules, 2017 - mdpi.com
The metabolites from the coumarin class, present in tissues of plants belonging mainly to the
Rutaceae and Apiaceae families, included compounds with high chemical diversity such as …

Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

Electrochemical and mechanochemical synthesis of dihydrofuro [3, 2-c] chromenones via intramolecular C sp3–H cross-dehydrogenative oxygenation within warfarin …

I Karmakar, G Brahmachari - Green Chemistry, 2022 - pubs.rsc.org
As a dual approach, we herein disclose electrochemical and mechanochemical methods for
the efficient and straightforward synthesis of a new series of functionalized dihydrofuro [3, 2 …