Optical trapping in vivo: theory, practice, and applications

IA Favre-Bulle, AB Stilgoe, EK Scott… - …, 2019 - degruyter.com
Since the time of their introduction, optical tweezers (OTs) have grown to be a powerful tool
in the hands of biologists. OTs use highly focused laser light to guide, manipulate, or sort …

Strategies for optical trapping in biological samples: Aiming at microrobotic surgeons

AI Bunea, J Glückstad - Laser & Photonics Reviews, 2019 - Wiley Online Library
Optical trapping and manipulation of objects down to the Ångstrom level has revolutionized
research at the smallest scales in all natural sciences. The flexibility of optical trapping …

Controlled transfer of transverse orbital angular momentum to optically trapped birefringent microparticles

AB Stilgoe, TA Nieminen, H Rubinsztein-Dunlop - Nature Photonics, 2022 - nature.com
The interaction between structured light beams possessing optical angular momentum and
small particles promises new opportunities for optical manipulation, such as the generation …

Light‐driven rotation of plasmonic nanomotors

L Shao, M Käll - Advanced Functional Materials, 2018 - Wiley Online Library
Colloidal metal nanocrystals exhibit distinct plasmonic resonances that can greatly enhance
optical forces and torques. This article highlights the recent application of such particles as …

Optical manipulation: advances for biophotonics in the 21st century

S Corsetti, K Dholakia - Journal of Biomedical Optics, 2021 - spiedigitallibrary.org
Significance: Optical trapping is a technique capable of applying minute forces that has
been applied to studies spanning single molecules up to microorganisms. Aim: The goal of …

Spin–orbit angular-momentum transfer from a nanogap surface plasmon to a trapped nanodiamond

H Fujiwara, K Sudo, Y Sunaba, C Pin, S Ishida… - Nano Letters, 2021 - ACS Publications
The ability to control the motion of single nanoparticles or molecules is currently one of the
major scientific and technological challenges. Despite tremendous progress in the field of …

Inverse design of plasmonic nanotweezers by topology optimization

D Nelson, S Kim, KB Crozier - ACS Photonics, 2023 - ACS Publications
We use topology optimization and adjoint sensitivity analysis to inversely design plasmonic
nanoapertures for nanoparticle optical trapping. Surprisingly, our algorithm produces a …

Rotational optical tweezers for active microrheometry within living cells

ML Watson, DL Brown, AB Stilgoe, JL Stow… - Optica, 2022 - opg.optica.org
Studying the mechanical properties of living cells provides opportunities to unravel the
physical phenomena that govern biological functions. Macropinocytosis is a cellular …

[HTML][HTML] Machine learning opens a doorway for microrheology with optical tweezers in living systems

MG Smith, J Radford, E Febrianto, J Ramírez… - AIP Advances, 2023 - pubs.aip.org
It has been argued that linear microrheology with optical tweezers (MOT) of living systems
“is not an option” because of the wide gap between the observation time required to collect …

Measuring local properties inside a cell‐mimicking structure using rotating optical tweezers

S Zhang, LJ Gibson, AB Stilgoe… - Journal of …, 2019 - Wiley Online Library
Exploring the rheological properties of intracellular materials is essential for understanding
cellular and subcellular processes. Optical traps have been widely used for physical …