[HTML][HTML] Spatially resolved transcriptomics: a comprehensive review of their technological advances, applications, and challenges

M Cheng, Y Jiang, J Xu, AFA Mentis, S Wang… - Journal of Genetics and …, 2023 - Elsevier
The ability to explore life kingdoms is largely driven by innovations and breakthroughs in
technology, from the invention of the microscope 350 years ago to the recent emergence of …

Spatial transcriptomics: technical aspects of recent developments and their applications in neuroscience and cancer research

HE Park, SH Jo, RH Lee, CP Macks, T Ku… - Advanced …, 2023 - Wiley Online Library
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …

STOmicsDB: a comprehensive database for spatial transcriptomics data sharing, analysis and visualization

Z Xu, W Wang, T Yang, L Li, X Ma, J Chen… - Nucleic acids …, 2024 - academic.oup.com
Recent technological developments in spatial transcriptomics allow researchers to measure
gene expression of cells and their spatial locations at the single-cell level, generating …

High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq

JK Benotmane, J Kueckelhaus, P Will, J Zhang… - Nature …, 2023 - nature.com
Spatial resolution of the T cell repertoire is essential for deciphering cancer-associated
immune dysfunction. Current spatially resolved transcriptomic technologies are unable to …

A lamprey neural cell type atlas illuminates the origins of the vertebrate brain

F Lamanna, F Hervas-Sotomayor, AP Oel… - Nature Ecology & …, 2023 - nature.com
The vertebrate brain emerged more than~ 500 million years ago in common evolutionary
ancestors. To systematically trace its cellular and molecular origins, we established a …

Mechanisms of kidney fibrosis and routes towards therapy

N Yamashita, R Kramann - Trends in Endocrinology & Metabolism, 2024 - cell.com
Kidney fibrosis is the final common pathway of virtually all chronic kidney diseases (CKDs)
and is therefore considered to be a promising therapeutic target for these conditions …

Custom microfluidic chip design enables cost-effective three-dimensional spatiotemporal transcriptomics with a wide field of view

J Zhu, K Pang, B Hu, R He, N Wang, Z Jiang, P Ji… - Nature Genetics, 2024 - nature.com
Spatial transcriptomic techniques offer unprecedented insights into the molecular
organization of complex tissues. However, integrating cost-effectiveness, high throughput, a …

Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain

Y Li, Z Li, C Wang, M Yang, Z He, F Wang, Y Zhang… - Cell, 2023 - cell.com
Different functional regions of brain are fundamental for basic neurophysiological activities.
However, the regional specification remains largely unexplored during human brain …

Spatial transcriptomics drives a new era in plant research

R Yin, K Xia, X Xu - The Plant Journal, 2023 - Wiley Online Library
Spatial transcriptomics drives a new era in plant research - Yin - 2023 - The Plant Journal - Wiley
Online Library Skip to Article Content Skip to Article Information Wiley Online Library Wiley …

Latent feature extraction with a prior-based self-attention framework for spatial transcriptomics

Z Li, X Chen, X Zhang, R Jiang, S Chen - Genome Research, 2023 - genome.cshlp.org
Rapid advances in spatial transcriptomics (ST) have revolutionized the interrogation of
spatial heterogeneity and increase the demand for comprehensive methods to effectively …