Mechanisms that regulate the function of the selectins and their ligands
D Vestweber, JE Blanks - Physiological reviews, 1999 - journals.physiology.org
Vestweber, Dietmar, and James E. Blanks. Mechanisms That Regulate the Function of the
Selectins and Their Ligands. Physiol. Rev. 79: 181–213, 1999.—Selectins are a family of …
Selectins and Their Ligands. Physiol. Rev. 79: 181–213, 1999.—Selectins are a family of …
CD123 as a therapeutic target in the treatment of hematological malignancies
U Testa, E Pelosi, G Castelli - Cancers, 2019 - mdpi.com
The interleukin-3 receptor alpha chain (IL-3Rα), more commonly referred to as CD123, is
widely overexpressed in various hematological malignancies, including acute myeloid …
widely overexpressed in various hematological malignancies, including acute myeloid …
CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies
U Testa, E Pelosi, A Frankel - Biomarker research, 2014 - Springer
Recent studies indicate that abnormalities of the alpha-chain of the interleukin-3 receptor (IL-
3RA or CD123) are frequently observed in some leukemic disorders and may contribute to …
3RA or CD123) are frequently observed in some leukemic disorders and may contribute to …
microRNA-222 controls neovascularization by regulating signal transducer and activator of transcription 5A expression
P Dentelli, A Rosso, F Orso, C Olgasi… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—Inflammatory stimuli released into atherosclerotic plaque microenvironment
regulate vessel formation by modulating gene expression and translation. microRNAs are a …
regulate vessel formation by modulating gene expression and translation. microRNAs are a …
The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signaling
SE Broughton, U Dhagat, TR Hercus… - Immunological …, 2012 - Wiley Online Library
Granulocyte–macrophage colony‐stimulating factor (GM–CSF), interleukin‐3 (IL‐3), and IL‐
5 are members of a discrete family of cytokines that regulates the growth, differentiation …
5 are members of a discrete family of cytokines that regulates the growth, differentiation …
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow
PS Frenette, S Subbarao, IB Mazo… - Proceedings of the …, 1998 - National Acad Sciences
The adhesive mechanisms allowing hematopoietic progenitor cells (HPC) homing to the
bone marrow (BM) after BM transplantation are poorly understood. We investigated the role …
bone marrow (BM) after BM transplantation are poorly understood. We investigated the role …
Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues.
KM Schweitzer, AM Dräger… - The American journal …, 1996 - ncbi.nlm.nih.gov
The first step in the homing of hematopoietic progenitor cells (HPCs) from the peripheral
blood to the bone marrow involves an adhesion molecule-dependent contact with human …
blood to the bone marrow involves an adhesion molecule-dependent contact with human …
Rapidly switchable universal CAR-T cells for treatment of CD123-positive leukemia
S Loff, J Dietrich, JE Meyer, J Riewaldt, J Spehr… - Molecular Therapy …, 2020 - cell.com
Chimeric antigen receptor T cells (CAR-T) targeting CD19 or B cell maturation antigen
(BCMA) are highly effective against B cell malignancies. However, application of CAR-T to …
(BCMA) are highly effective against B cell malignancies. However, application of CAR-T to …
Enhancement of neovascularization with cord blood CD133+ cell-derived endothelial progenitor cell transplantation
The endothelial progenitor cells (EPCs) are responsible for postnatal vasculogenesis in
physiological and pathological neovascularization and have been used for attenuating …
physiological and pathological neovascularization and have been used for attenuating …
Activated Stat5 trafficking via endothelial cell-derived extracellular vesicles controls IL-3 pro-angiogenic paracrine action
G Lombardo, P Dentelli, G Togliatto, A Rosso, M Gili… - Scientific reports, 2016 - nature.com
Soluble factors and cell-derived extracellular vesicles (EVs) control vascular cell fate during
inflammation. The present study investigates the impact of Interleukin 3 (IL-3) on EV release …
inflammation. The present study investigates the impact of Interleukin 3 (IL-3) on EV release …