Now that we are over 10 years into the HAART era in resource-rich countries the major clinical impact of this therapy on reduced AIDS events and AIDS deaths has been well …
JD Lundgren, AG Babiker, F Gordin… - The New England …, 2015 - europepmc.org
Background Data from randomized trials are lacking on the benefits and risks of initiating antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …
Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …
J Neuhaus, DR Jacobs Jr, JV Baker… - The Journal of …, 2010 - academic.oup.com
Abstract (See the article by Kalayjian et al, on pages 1796–1805, and the editorial commentary by Dubé and Sattler, on pages 1783–1785.) Background. Human …
DA Duprez, J Neuhaus, LH Kuller, R Tracy, W Belloso… - 2012 - journals.plos.org
Background The SMART study was a trial of intermittent use of antiretroviral therapy (ART)(drug conservation [DC]) versus continuous use of ART (viral suppression [VS]) as a …
It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular …
Objectives To estimate life expectancy for people with HIV undergoing treatment compared with life expectancy in the general population and to assess the impact on life expectancy of …
B Grund, JV Baker, SG Deeks, J Wolfson, D Wentworth… - PloS one, 2016 - journals.plos.org
Background Despite effective antiretroviral treatment (ART), HIV-positive individuals are at increased risk of serious non-AIDS conditions (cardiovascular, liver and renal disease, and …
AD Nordell, M McKenna, ÁH Borges… - Journal of the …, 2014 - Am Heart Assoc
Background In the general population, raised levels of inflammatory markers are stronger predictors of fatal than nonfatal cardiovascular disease (CVD) events. People with HIV have …