Group 2 innate lymphoid cells (ILC2s) are involved in human diseases, such as allergy,
atopic dermatitis and nasal polyposis, but their function in human cancer remains unclear …

Non-muscle–invasive bladder cancer (NMIBC) is a highly recurrent tumor despite
intravesical immunotherapy instillation with the bacillus Calmette-Guérin (BCG) vaccine. In a …

Background At present, research on immunogenic cell death (ICD) is mainly associated with
cancer therapy. Little is known about the role of ICD in cardiovascular disease, especially in …

Natural and synthetic biomaterials are increasingly being used for the development of
vaccines and immunotherapies as alternatives to traditional live-attenuated formulations due …

Recruitment and activation of CD8 T cells occur through specific triggering of T cell receptor
(TCR) by peptide-bound human leucocyte antigen (HLA) ligands. Within the generated …

Background Regulated cell death plays a very important role in atherosclerosis (AS).
Despite a large number of studies, there is a lack of literature on immunogenic cell death …

Introduction The avidity of the T-cell receptor (TCR) for antigenic peptides presented by the
MHC (pMHC) on cells is an essential parameter for efficient T cell-mediated immunity. Yet …

Purpose: Patients with cancer benefit increasingly from T-cell–based therapies, such as
adoptive T-cell transfer, checkpoint blockade, or vaccination. We have previously shown that …

Experimental models demonstrated that therapeutic induction of CD8 T cell responses may
offer protection against tumors or infectious diseases providing that T cells have sufficiently …

Background: Macrophages play an important role in the occurrence and development of
atherosclerosis. However, few existing studies have deliberately analyzed the changes in …