The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Pathogenesis and virulence of flavivirus infections

SW van Leur, T Heunis, D Munnur, S Sanyal - Virulence, 2021 - Taylor & Francis
The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus

E Branche, YT Wang, KM Viramontes… - Nature …, 2022 - nature.com
The emergence of Zika virus (ZIKV) as a global health threat has highlighted the unmet need
for ZIKV-specific vaccines and antiviral treatments. ZIKV infects dendritic cells (DC), which …

The citrus flavonoid naringenin impairs the in vitro infection of human cells by Zika virus

AHD Cataneo, D Kuczera, AC Koishi, C Zanluca… - Scientific Reports, 2019 - nature.com
The Zika virus (ZIKV) is an arthropod-borne virus that belongs to the Flaviviridae family. The
ZIKV infection is usually asymptomatic or is associated with mild clinical manifestations; …

Pathogenesis and manifestations of Zika virus-associated ocular diseases

BA Labib, DGI Chigbu - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
Zika virus (ZIKV) is mosquito-borne flavivirus that caused a significant public health concern
in French Polynesia and South America. The two major complications that gained the most …

Zika virus-induced neuronal apoptosis via increased mitochondrial fragmentation

S Yang, K Gorshkov, EM Lee, M Xu, YS Cheng… - Frontiers in …, 2020 - frontiersin.org
The 2015 to 2016 outbreak of Zika virus (ZIKV) infections in the Americas coincided with a
dramatic increase in neurodevelopmental abnormalities, including fetal microcephaly, in …

Metabolic response to CNS infection with flaviviruses

M Dobrzyńska, A Moniuszko-Malinowska… - Journal of …, 2023 - Springer
Flaviviruses are arthropod-borne RNA viruses found worldwide that, when introduced into
the human body, cause diseases, including neuroinfections, that can lead to serious …

Comprehensive immunoprofiling of pediatric zika reveals key role for monocytes in the acute phase and no effect of prior dengue virus infection

D Michlmayr, EY Kim, AH Rahman, R Raghunathan… - Cell reports, 2020 - cell.com
Zika virus (ZIKV) is an emerging, mosquito-borne flavivirus responsible for recent epidemics
across the Americas, and it is closely related to dengue virus (DENV). Here, we study …

Probing molecular insights into Zika virus–host interactions

I Lee, S Bos, G Li, S Wang, G Gadea, P Desprès… - Viruses, 2018 - mdpi.com
The recent Zika virus (ZIKV) outbreak in the Americas surprised all of us because of its rapid
spread and association with neurologic disorders including fetal microcephaly, brain and …

An update on sexual transmission of Zika virus

H Sakkas, P Bozidis, X Giannakopoulos, N Sofikitis… - Pathogens, 2018 - mdpi.com
Zika virus (ZIKV) is a single-stranded RNA virus belonging to the arthropod-borne
flaviviruses (arboviruses) which are mainly transmitted by blood-sucking mosquitoes of the …