Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

[HTML][HTML] Rapid identification of pathogenic bacteria using Raman spectroscopy and deep learning

CS Ho, N Jean, CA Hogan, L Blackmon… - Nature …, 2019 - nature.com
Raman optical spectroscopy promises label-free bacterial detection, identification, and
antibiotic susceptibility testing in a single step. However, achieving clinically relevant speeds …

Recent progresses in machine learning assisted Raman spectroscopy

Y Qi, D Hu, Y Jiang, Z Wu, M Zheng… - Advanced Optical …, 2023 - Wiley Online Library
With the development of Raman spectroscopy and the expansion of its application domains,
conventional methods for spectral data analysis have manifested many limitations. Exploring …

Recent developments in Raman spectral analysis of microbial single cells: Techniques and applications

H Jayan, H Pu, DW Sun - Critical Reviews in Food Science and …, 2022 - Taylor & Francis
The conventional microbial cell analyses are mostly population-averaged methods that
conceal the characteristics of single-cell in the community. Single-cell analysis can provide …

Ramanome technology platform for label-free screening and sorting of microbial cell factories at single-cell resolution

Y He, X Wang, B Ma, J Xu - Biotechnology Advances, 2019 - Elsevier
Phenotypic profiling of natural, engineered or synthetic cells has increasingly become a
bottleneck in the mining and engineering of cell factories. Single-cell phenotyping …

Raman‐activated sorting of antibiotic‐resistant bacteria in human gut microbiota

Y Wang, J Xu, L Kong, B Li, H Li… - Environmental …, 2020 - Wiley Online Library
The antibiotic‐resistant bacteria (ARB) and antibiotic‐resistant genes (ARGs) in human gut
microbiota have significant impact on human health. While high throughput metagenomic …

Development overview of Raman-activated cell sorting devoted to bacterial detection at single-cell level

S Yan, J Qiu, L Guo, D Li, D Xu, Q Liu - Applied Microbiology and …, 2021 - Springer
Understanding the metabolic interactions between bacteria in natural habitat at the single-
cell level and the contribution of individual cell to their functions is essential for exploring the …

[HTML][HTML] Optical methods for bacterial detection and characterization

C McGoverin, C Steed, A Esan, J Robertson, S Swift… - APL Photonics, 2021 - pubs.aip.org
Rapid identification and enumeration of bacteria are critical, given the surge of antibiotic-
resistance, global exchange of food products, and the use of bacteria for bioremediation …

Detection of multi-resistant clinical strains of E. coli with Raman spectroscopy

A Nakar, A Pistiki, O Ryabchykov, T Bocklitz… - Analytical and …, 2022 - Springer
In recent years, we have seen a steady rise in the prevalence of antibiotic-resistant bacteria.
This creates many challenges in treating patients who carry these infections, as well as …