Inflammation is the response of the immune system to harmful stimuli such as tissue injury,
infection or toxic chemicals, which has the aim of eliminating irritants or pathogenic …

Ion channels play fundamental roles in both excitable and non-excitable tissues and
therefore constitute attractive drug targets for myriad neurological, cardiovascular and …

The diversity of venomous organisms and the toxins they produce have been increasingly
investigated, but taxonomic bias remains important. Neogastropods, a group of marine …

In the last decades Blue Growth policy in european and non-european countries produced a
great impulse in applied marine sciences, comprehending the research of new bioactive …

Somatostatin (SS) is a peptide hormone with diverse physiological roles. By investigating a
deep-water clade of fish-hunting cone snails, we show that predator-prey evolution has …

Transient receptor potential vanilloid 1 (TRPV1) ion channel is a classic analgesic target, but
antagonists of TRPV1 failed in clinical trials due to their side effects like hyperthermia. Here …

Animal venom peptides represent valuable compounds for biomedical exploration. The
venoms of marine cone snails constitute a particularly rich source of peptide toxins, known …

The therapeutic potential of venom-derived drugs is evident today. Currently, several
significant drugs are FDA approved for human use that descend directly from animal venom …

The purpose of our review is to briefly show what different compounds of marine origin, from
low molecular weight ones to peptides and proteins, offer for understanding the structure …

Oxaliplatin is a third-generation platinum drug and is widely used as a first-line therapy for
the treatment of colorectal cancer (CRC). However, a large number of patients receiving …